Two Cases of Pulmonary Infection due to A. xylosoxidans Infection in an Immunocompentent Patient.

Lee, Ju Hyun; Nam, Dong Hyuk; Kim, Do Hyun; Kim, Sun Hye; Kim, Ha Na; Han, Chang Hun; Lee, Sun Min; Kim, Chong Ju

doi:2008.64.1.33

Tuberc Respir Dis > Volume 64(1); 2008 > Article

Case Report

Tuberculosis and Respiratory Diseases 2008;64(1):33-38.
DOI: https://doi.org/10.4046/trd.2008.64.1.33 Published online January 1, 2008.

Two Cases of Pulmonary Infection due to A. xylosoxidans Infection in an Immunocompentent Patient.

Ju Hyun Lee, Dong Hyuk Nam, Do Hyun Kim, Sun Hye Kim, Ha Na Kim, Chang Hun Han, Sun Min Lee, Chong Ju Kim

Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea. kom2d@netsgo.com

Abstract

lcaligenes xylosoxidans is a catalase and oxidase positive, motile, nonfermentative and gram-negative rod bacterium. A. xylosoxidans infection is a rare cause of pulmonary infection and little information concerning treatment is available. The majority of patients that develop A. xylosoxidans infection belong to a high-risk group due to an immunocompromised condition or due to pulmonary cystic fibrosis. We report two rare cases of immunocompentent patients that developed a pulmonary infection due to A. xylosoxidans. A 77-year-old man was admitted with a lung abscess. The patient denied having any prior medical illness. A culture of bronchial washing fluid showed the presence of A. xylosoxidans. Despite appropriate antibiotic treatment, the patient died from acute respiratory distress syndrome (ARDS). Another patient, a 61-year-old man without an underlying disease, was admitted with empyema. Under the condition of a closed thoracostomy, a high fever persisted and the empyema was also aggravated. A. xylosoxidans was detected from a culture of pleural fluid. Susceptible antibiotic treatment was provided and surgical intervention was performed. We report these cases with a review of the literature.

Key Words: Alcaligenes xylosoxidans, Pulmonary infection, Gram-negative rod