Fatal Tumor Lysis Syndrome During Chemotherapy in Small Cell Lung Cancer. |
Eun Hee Kook, Min Soo Kim, Se Han Ahn, Se Young Jeon, Jung Ho Yoon, Min Sung Han, Cheol Hyeon Kim, Jae Cheol Lee |
Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea. jclee@kcch.re.kr |
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Abstract |
Tumor lysis syndrome is a life-threatening complication of anti-cancer therapy that typically occurs in patients with large, rapidly growing and treatment-sensitive tumors such as high-grade lymphomas and acute leukemias. However, its incidence in solid tumors has been known to be very low. Tumor lysis syndrome in solid tumors has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of fatal tumor lysis syndrome developed during chemotherapy in extensive-stage small cell lung cancer, along with a brief review of the relevant literature considering the rarity of this manifestation in solid tumor. |
Key Words:
Small cell lung cancer, Tumor lysis syndrome |
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