A Clinical Study on the Antipyratic Action of Anti Tb Chemotherapy

Ham, Sung Sook; Kim, Hyung Duck

doi:1969.16.3.27

Tuberc Respir Dis > Volume 16(3); 1969 > Article

Original Article

Tuberculosis and Respiratory Diseases 1969;16(3):27-31.
DOI: https://doi.org/10.4046/trd.1969.16.3.27 Published online September 1, 1969.

A Clinical Study on the Antipyratic Action of Anti Tb Chemotherapy

Sung Sook Ham, Hyung Duck Kim

Department of Chest, Medicine Yonsei University, College of Medicine, Seoul, Korea

결핵의 화학요법과 해열에 대한 관찰

함성숙, 김형덕

Abstract

The subjects were taken at random among the 960 in-patients of minimal, moderately advanced and far advanced pulmonary tuberculosis patients, 'who had been admitted to chest clinic of Severance hospitalin last two years. Those who had no previous anti-Tb chemotherapy, no intra or extrapulmoary complications and no history of the administration of steroid or ordinary antibiotics were 194, 20.2% of the whole number of 960. Among these 194 patients, 73(37.6 %) had the temperature of above normal limits. Miliary tuberculosis of the lung was not included here, and the most of the patients were adult typed tuberculosis. The fever was usually subsided aróund 4 days (1-15days) after the administration of triple primary anti-Tb drugs. We also have observed that those who had anemia were more prone to febrile reactions. Among the 73 febrile patients, 61 patients (83%) had the hemoglobin concentration of below 10 gm %. Besides, there were no particular relationships noticed between the febrile reaction of tuberculosis and the presence of AFB in sputum, daily amount of sputum, leukocyte COUl1ts in the peripheral blood or the presence of hemoptysis.