Serum Concentrations of Vitamine D Metabolites in Patients with Untreated Tuberculosis |
Suk Hoon Lee, Ho Yeon Jung, Chul Jun Choi, Jee Hong Yoo, Hong Mo Kang, Won Dong Kim |
Department of Internal Medicine, Kyung Hee University, School of Medicine, Seoul, Korea |
한국인 결핵환자에서 비타민 D 대사물의 혈청농도 |
이석훈, 정호연, 최철준, 유지홍, 강홍모, 김원동 |
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Abstract |
T o evaluate the status of serum vitamin D metabolites in patients with untreated tuberculosis, the serum levels of 25-OHD3 and 1.25-(OH)2D3 in 20 patients with untreated pulmonary tuberculosis and tuberculous pleurisy were compared with those in age and sex matched 20 healthy controls.
The results were as follows;
1) Mean serum 25-OHD3 concentrations in tubercul osis and control group were 14.6±7.5 ng/ ml and 15.0±5.0 ng/ ml respectively, and there was no significant difference (P > 1.0).
2) Mean serum 1.25-(OH)2D3 concentrations in tubercul osis a nd control group were 28.5±9.8 pg/ ml and 30.2±10.3 pg/ ml respectively, a nd there was no significant di fference (P > 1.0).
3) Mean serum 25-OHD3 concentration in patients with tuberculous pleurisy was significantly lower than that in control subjects (P < 0.05).
This study suggested that there was no significant association between tuberculosis and serum vitamin D metabolites in Korean patients, but vitamin D might be associated with tuberculous pleurisy. |
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