Sarcoidosis Occured after Treatment of Tuberculous Lymphadenitis.

Lee, Hyo Jeong; Yoon, Sun Young; Han, Ji Min; An, Ji Hyun; Lee, Jeong Ju; Choi, Chang Min; Oh, Yeon Mok; Shim, Tae Sun; Lee, Sang Do; Kim, Woo Sung; Kim, Dong Soon; Song, Jin Woo

doi:2011.70.5.433

Tuberc Respir Dis > Volume 70(5); 2011 > Article

Case Report

Tuberculosis and Respiratory Diseases 2011;70(5):433-437.
DOI: https://doi.org/10.4046/trd.2011.70.5.433 Published online May 1, 2011.

Sarcoidosis Occured after Treatment of Tuberculous Lymphadenitis.

Hyo Jeong Lee, Sun Young Yoon, Ji Min Han, Ji Hyun An, Jeong Ju Lee, Chang Min Choi, Yeon Mok Oh, Tae Sun Shim, Sang Do Lee, Woo Sung Kim, Dong Soon Kim, Jin Woo Song

¹Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. skysong3@hanmail.net
²Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Sarcoidosis is a multisystemic disorder characterized by the presence of non-caseating granulomas in the involved organ. Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis and is characterized by granuloma with caseous necrosis. The clinical and histological similarity between sarcoidosis and tuberculosis has stimulated research searching for an association between mycobacterium and sarcoidosis. We report a case of a 38-year-old male with sarcoidosis that developed soon after treatment of tuberculous lymphadenitis. He was diagnosed as tuberculous lymphadenitis by microbiological confirmation. He showed clinical improvement after treatment for tuberculosis. One year later, his chest radiography showed bilateral hilar enlargement with diffuse bilateral nodules. A noncaseating granuloma was confirmed by endobronchial ultrasound guided transbronchial needle aspiration and he was diagnosed with sarcoidosis. To our knowledge, this is the first report describing sarcoidosis after treatment of tuberculosis in South Korea.

Key Words: Sarcoidosis, Tuberculosis, Granuloma