Prostatic Cancer Presenting as an Isolated Large Lung Mass.

No, Hee Sun; Lee, Jong Hwan; Ahn, Young; Na, Im Il; Kim, Hye Ryoun; Kim, Cheol Hyeon; Koh, Jae Soo; Lee, Jae Cheol

doi:2010.68.5.290

Tuberc Respir Dis > Volume 68(5); 2010 > Article

Case Report

Tuberculosis and Respiratory Diseases 2010;68(5):290-293.
DOI: https://doi.org/10.4046/trd.2010.68.5.290 Published online May 1, 2010.

Prostatic Cancer Presenting as an Isolated Large Lung Mass.

Hee Sun No, Jong Hwan Lee, Young Ahn, Im Il Na, Hye Ryoun Kim, Cheol Hyeon Kim, Jae Soo Koh, Jae Cheol Lee

¹Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea. jclee@kcch.re.kr
²Department of Pathology, Korea Cancer Center Hospital, Seoul, Korea.

Abstract

A hidden primary tumor presenting as an isolated lung mass is a diagnostic challenge to physicians because the diagnosis of lung cancer is likely to be made if the histologic findings are not inconsistent with lung cancer. A large lung mass was found incidentally in a 59-year-old man. Although adenocarcinoma was diagnosed by percutaneous needle biopsy, thyroid transcription factor-1 (TTF-1) immunostaining was negative, raising suspicion that there was another primary site. There was no abnormal finding except for the lung mass on a 18FDG-PET/CT scan and the patient did not complain of any discomfort. Finally, prostatic cancer was confirmed through the study of tumor markers and prostate-specific antigen (PSA) immunostaining. Because of the rare presentation of a single lung mass in malignancies that have another primary site, physicians should carefully review all data before making a final diagnosis of lung cancer.

Key Words: Metastasis, Prostatic Neoplasms, Thyroid Transcription Factor 1, Tumor Markers, Biological