A Case of Idiopathic Hypereosinophilic Syndrome Presenting Acute Pulmonary Edema.

Yu, Kyong Sul; Kim, Yeon Jae; Seo, Hyang Eun; Yoon, Hye Jin; Do, Yun Kyung; Lee, Byung Ki; Kim, Won Ho

doi:2002.52.2.166

Tuberc Respir Dis > Volume 52(2); 2002 > Article

Case Report

Tuberculosis and Respiratory Diseases 2002;52(2):166-173.
DOI: https://doi.org/10.4046/trd.2002.52.2.166 Published online February 1, 2002.

A Case of Idiopathic Hypereosinophilic Syndrome Presenting Acute Pulmonary Edema.

Kyong Sul Yu, Yeon Jae Kim, Hyang Eun Seo, Hye Jin Yoon, Yun Kyung Do, Byung Ki Lee, Won Ho Kim

Department of Internal Medicine, Fatima Hospital, Daegu, Korea. persimmonkim@lycos.co.kr

Abstract

Transient peripheral eosinophilia occurs in several disorders, such as allergic diseases, cancer, and parasitic in fections. However, in most cases, their persence is not accompanied by tissue destruction or organ dysfunc tion. In certain disease states, eosinophils can accumulate in any organ in the body and cause tissue destruction as a result of the eosinophil infiltration or the toxic effects of the degranulated proinflammatory products. Idiopathic hypereosinopilic syndrome is a rare disorder characterized by persistent eosinophilia of an unknown origin, usually associated with a dysfunction of organs such as the heart, lung, skin, and nervous system. Idiopathic hypereosinophilic syndrome usually has an indolent course over a period of several months. However, in some cases, they have grave symptoms if vital organs such as heart and lung are infiltrated. Here we report a case of idiopathic hypereosinophilic syndrome presenting acute pulmonary edema involving the heart, bone marrow, and lung with a review of the relevant literatures.

Key Words: Idiopathic hypereosinophilic syndrome, Acute pulmonary edema