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Original Article
COPD, Asthma
Association of Nutritional Intake with Physical Activity and Handgrip Strength in Individuals with Airflow Limitation
I Re Heo, Tae Hoon Kim, Jong Hwan Jeong, et al.
Tuberc Respir Dis. 2025;88(1):120-129.   Published online October 11, 2024
Background: We investigated whether nutritional intake is associated with physical activity (PA) and handgrip strength (HGS) in individuals with airflow limitation. Methods: This study analyzed data from the 2014 and 2016 Korean National Health and Nutrition Examination Survey. We assessed total protein intake (g/day), caloric intake (kcal/day), and other nutritional intakes, using a 24-hour dietary recall questionnaire. HGS was measured three...
Original Article
Interstitial Lung Disease
Regenerative Capacity of Alveolar Type 2 Cells Is Proportionally Reduced Following Disease Progression in Idiopathic Pulmonary Fibrosis-Derived Organoid Cultures
Hyeon Kyu Choi, Gaeul Bang, Ju Hye Shin, et al.
Tuberc Respir Dis. 2025;88(1):130-137.   Published online September 27, 2024
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease that culminates in respiratory failure and death due to irreversible scarring of the distal lung. While initially considered a chronic inflammatory disorder, the aberrant function of the alveolar epithelium is now acknowledged as playing a central role in the pathophysiology of IPF. This study aimed to investigate the regenerative...
Original Article
Lung Cancer
KEAP1-NRF2 Pathway as a Novel Therapeutic Target for EGFR-Mutant Non-small Cell Lung Cancer
Jae-Sun Choi, Hye-Min Kang, Kiyong Na, et al.
Tuberc Respir Dis. 2025;88(1):138-149.   Published online September 23, 2024
Background: Kelch-like ECH-associated protein 1 (KEAP1)–nuclear factor erythroid- 2-related factor 2 (NRF2) pathway is a major regulator protecting cells from oxidative and metabolic stress. Studies have revealed that this pathway is involved in mediating resistance to cytotoxic chemotherapy and immunotherapy; however, its implications in oncogene-addicted tumors are largely unknown. This study aimed to elucidate whether this pathway could be a...
Original Article
Tuberculosis
Diagnostic Accuracy of BD MAX MDR-TB Assay Performed on Bronchoscopy Specimens in Patients with Suspected Pulmonary Tuberculosis
Sung Jun Ko, Kui Hyun Yoon
Tuberc Respir Dis. 2025;88(1):150-158.   Published online September 23, 2024
Background: Several novel molecular platforms using nucleic acid amplification tests have been developed for the diagnosis of pulmonary tuberculosis (PTB) and rapid detection of isoniazid and rifampin resistance. Among them, the BD MAX MDR-TB assay (BD MAX) has shown high sensitivity and specificity; however, its diagnostic accuracy performed on bronchoscopy specimens has not been reported. Methods: We retrospectively reviewed the medical...
Original Article
Tuberculosis
Clinical Profiles of Multidrug-Resistant and Rifampicin-Monoresistant Tuberculosis in Korea, 2018–2021: A Nationwide Cross-Sectional Study
Jinsoo Min, Yousang Ko, Hyung Woo Kim, et al.
Tuberc Respir Dis. 2025;88(1):159-169.   Published online September 23, 2024
Background: This study aimed to identify the clinical characteristics of multidrug-resistant/ rifampicin-resistant tuberculosis (MDR/RR-TB) in the Republic of Korea. Methods: Data of notified people with tuberculosis between July 2018 and December 2021 were retrieved from the Korea Tuberculosis Cohort database. MDR/RR-TB was further categorized according to isoniazid susceptibility as follows: multidrug-resistant tuberculosis (MDR-TB), rifampicin-monoresistant tuberculosis (RMR-TB), and RR-TB if susceptibility to...
Original Article
Tuberculosis
High-Dose Rifampicin for 3 Months after Culture Conversion for Drug-Susceptible Pulmonary Tuberculosis
Nakwon Kwak, Joong-Yub Kim, Hyung-Jun Kim, et al.
Tuberc Respir Dis. 2025;88(1):170-180.   Published online September 27, 2024
Background: This study aimed to determine whether a shorter high-dose rifampicin regimen is non-inferior to the standard 6-month tuberculosis regimen. Methods: This multicenter, randomized, open-label, non-inferiority trial enrolled participants with respiratory specimen positivity by Xpert MTB/RIF assay or Mycobacterium tuberculosis culture without rifampicin-resistance. Participants were randomized at 1:1 to the investigational or control group. The investigational group received high-dose rifampicin (30...
Original Article
Miscellaneous
Dry Medical Thoracoscopy with Artificial Pneumothorax Induction Using Veress Needle
Nai-Chien Huan, Sze Shyang Kho, Larry Ellee Nyanti, et al.
Tuberc Respir Dis. 2025;88(1):181-189.   Published online November 14, 2024
Background: In the absence of significant pleural effusion, conventional medical thoracoscopy (MT) is often not feasible due to the risk of lung injury. Dry MT mitigates these risks by inducing artificial pneumothorax through needle insufflation or blunt dissection. Although the Veress needle is commonly used by surgeons to create pneumoperitoneum before laparoscopic surgeries, its application in dry MT has not...
Current Issue
Volume 88(1); Jan 2025
Original Articles
Prevalence of New Frailty at Hospital Discharge in Severe COVID-19 Survivors and Its Associated Factors
Jong Hwan Jeong, Manbong Heo, Sunghoon Park, Su Hwan Lee, Onyu Park, Taehwa Kim, Hye Ju Yeo, Jin Ho Jang, Woo Hyun Cho, Jung-Wan Yoo
Received October 17, 2024   Accepted November 27, 2024   Published online December 5, 2024   
DOI: https://doi.org/10.4046/trd.2024.0160    [Epub ahead of print]
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Letter to the Editor
Request for Study Design Modification in Examining Nutritional Intake and Muscle Strength in Individuals with Airflow Limitation
Ming-Che Chang, Chii-Lan Lin, Fong-Fong Tsai, Hwei-Mei Tai, Chih-Wei Kuo, Hon-Kwong Ma, Chih-Chung Shiao
Received November 8, 2024   Accepted November 19, 2024   Published online November 25, 2024   
DOI: https://doi.org/10.4046/trd.2024.0171    [Epub ahead of print]
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Original Articles
Features of Lung Cyst in Birt-Hogg-Dubé Syndrome from Patients with Multiple Lung Cysts
Yong Jun Choi, Hye Jung Park, Chi Young Kim, Bo Mi Jung, Jae Hwa Cho, Min Kwang Byun
Received April 1, 2024   Accepted November 19, 2024   Published online November 25, 2024   
DOI: https://doi.org/10.4046/trd.2024.0045    [Epub ahead of print]
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Tuberculosis and
Respiratory Diseases

Print ISSN: 1738-3536
Online ISSN: 2005-6184

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