Original Article
Clonal Hematopoiesis of Indeterminate Potential Is Associated with Current Smoking Status and History of Exacerbation in Patients with Chronic Obstructive Pulmonary Disease
Jung-Kyu Lee, Hongyul An, Youngil Koh, et al.
Tuberc Respir Dis. 2024;87(3):309-318.   Published online February 6, 2024
Background: There is limited data regarding the clinical outcomes of clonal hematopoiesis of indeterminate potential (CHIP) in patients with chronic obstructive pulmonary disease (COPD). This study aimed to evaluate the clinical significance of CHIP as a COPD biomarker. Methods: This retrospective study was conducted on patients with COPD who were enrolled prospectively in the Seoul National University Hospital Airway Registry from...
Original Article
Inhaled Corticosteroids May Not Affect the Clinical Outcomes of Pneumonia in Patients with Chronic Obstructive Pulmonary Disease
Min-Seok Chang, In-So Cho, Iseul Yu, et al.
Tuberc Respir Dis. 2024;87(3):319-328.   Published online February 19, 2024
Background: Although inhaled corticosteroids (ICS) is reportedly associated with a higher risk of pneumonia in chronic obstructive pulmonary disease (COPD), the clinical implications of ICS have not been sufficiently verified to determine their effect on the prognosis of pneumonia. Methods: The electronic health records of patients hospitalized for pneumonia with underlying COPD were retrospectively reviewed. Pneumonia was confirmed using chest radiography...
Original Article
Lack of Association between Inhaled Corticosteroid Use Based on the Exhaled Nitric Oxide and Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Bo-Guen Kim, Sun Hye Shin, Jung-Wan Yoo, et al.
Tuberc Respir Dis. 2024;87(3):329-337.   Published online March 5, 2024
Background: Fractional exhaled nitric oxide (FeNO) is known to useful biomarker for detecting eosinophilic airway inflammation. However, there is a lack of evidence regarding the role of FeNO in chronic obstructive pulmonary disease (COPD). We aimed to assess whether elevated FeNO and its impact on treatment change into an inhaled corticosteroid (ICS)-containing regimen and association with acute exacerbation (AE) in...
Original Article
Critical Care Medicine
Age Distribution and Clinical Results of Critically Ill Patients above 65-Year-Old in an Aging Society: A Retrospective Cohort Study
Song I Lee, Jin Won Huh, Sang-Bum Hong, et al.
Tuberc Respir Dis. 2024;87(3):338-348.   Published online February 29, 2024
Background: Increasing age has been observed among patients admitted to the intensive care unit (ICU). Age traditionally considered a risk factor for ICU mortality. We investigated how the epidemiology and clinical outcomes of older ICU patients have changed over a decade. Methods: We analyzed patients admitted to the ICU at a university hospital in Seoul, South Korea. We defined patients aged...
Original Article
Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Thailand: 6-Year Retrospective Study
Pattarin Pirompanich, Ornnicha Sathitakorn, Teeraphan Suppakomonnun, et al.
Tuberc Respir Dis. 2024;87(3):349-356.   Published online February 29, 2024
Background: Acute pulmonary embolism (APE) is a fatal disease with varying clinical characteristics and imaging. The aim of this study was to define the clinical characteristics, risk factors, and outcomes in patients with APE at a university hospital in Thailand. Methods: Patients diagnosed with APE and admitted to our institute between January 1, 2017 and December 31, 2022 were retrospectively enrolled....
Original Article
Association between the Risk of Obstructive Sleep Apnea and Lung Function: Korea National Health and Nutrition Examination Survey
Jinwoo Seok, Hee-Young Yoon
Tuberc Respir Dis. 2024;87(3):357-367.   Published online March 18, 2024
Background: Obstructive sleep apnea (OSA) is a prevalent sleep disorder associated with various health issues. Although some studies have suggested an association between reduced lung function and OSA, this association remains unclear. Our study aimed to explore this relationship using data from a nationally representative population- based survey. Methods: We performed an analysis of data from the 2019 Korea National Health...
Original Article
Usefulness of Impulse Oscillometry in Predicting the Severity of Bronchiectasis
Ji Soo Choi, Se Hyun Kwak, Min Chul Kim, et al.
Tuberc Respir Dis. 2024;87(3):368-377.   Published online April 30, 2024
Background: Bronchiectasis is a chronic respiratory disease that leads to airway inflammation, destruction, and airflow limitation, which reflects its severity. Impulse oscillometry (IOS) is a non-invasive method that uses sound waves to estimate lung function and airway resistance. The aim of this study was to assess the usefulness of IOS in predicting the severity of bronchiectasis. Methods: We retrospectively reviewed the...
Original Article
Pleural Diseases
Intrapleural Fibrinolysis with Urokinase versus Alteplase in Complicated Pleural Effusions and Empyema: A Prospective Randomized Controlled Trial
Sudipt Adhikari, Vikas Marwah, Robin Choudhary, et al.
Tuberc Respir Dis. 2024;87(3):378-385.   Published online March 7, 2024
Background: Intrapleural fibrinolytic therapy (IPFT) has been used as an effective agent since 1949 for managing complicated pleural effusion and empyema. Several agents, such as streptokinase, urokinase (UK), and recombinant tissue plasminogen activator (rt-PA), have been found to be effective with variable effectiveness. However, a head-tohead controlled trial comparing the efficacy of the most frequently used agents, i.e., UK and...
Original Article
Epidemiological Characteristics of Nontuberculous Mycobacterial Pulmonary Disease in South Korea: A Meta-analysis of Individual Participant Data
Geunin Lee, Sol Kim, Shihwan Chang, et al.
Tuberc Respir Dis. 2024;87(3):386-397.   Published online April 9, 2024
Background: Despite the global increase in nontuberculous mycobacterial pulmonary disease (NTM-PD), clinical characteristics show geographical variations. We investigated the clinical characteristics of patients with NTM-PD in South Korea. Methods: We systematically reviewed articles concerning patients with NTM-PD in South Korea until February 2022. Individual participant data, regardless of treatment, were collected using a standard case report form. Results: Data of 6,489 patients...
Original Article
Bioinformatics Study and Experimental Evaluation of miR-182, and miR-34 Expression Profiles in Tuberculosis and Lung Cancer
Leila Alimardanian, Bahram Mohammad Soltani, Shiva Irani, et al.
Tuberc Respir Dis. 2024;87(3):398-408.   Published online April 15, 2024
Background: Lung cancer is one of the most dangerous cancers and tuberculosis is one of the deadliest infectious diseases in the world. Many studies have confirmed the connection between lung cancer and tuberculosis, and also the microRNAs (miRNAs) that play a major role in the development of these two diseases. This study aims to use different databases to find effective...
Original Articles
Inhaled Corticosteroids and the Risk of Nontuberculous Mycobacterial Infection in Chronic Airway Disease: A Nationwide Population-Based Study
Eun Chong Yoon, Hyewon Lee, Hee-Young Yoon
Received March 20, 2024   Accepted May 29, 2024   Published online June 5, 2024   
DOI: https://doi.org/10.4046/trd.2024.0038    [Epub ahead of print]
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Immune Checkpoint Inhibitor Score Predicts Survival Benefit of Immunotherapy in Patients with Non-small Cell Lung Cancer
Da Hyun Kang, Chang-Min Choi, Cheol-Kyu Park, In-Jae Oh, Young-Chul Kim, Seong Hoon Yoon, Yoonjoo Kim, Jeong Eun Lee
Received December 6, 2023   Accepted May 12, 2024   Published online May 14, 2024   
DOI: https://doi.org/10.4046/trd.2023.0190    [Epub ahead of print]
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Prevalence and Characteristics of Tuberculosis in the Korean Homeless Population Based on Nationwide Tuberculosis Screening
Heesang Han, Ji-Hee Lee, Sung Jun Chung, Beong Ki Kim, Yedham Kang, Hangseok Choi, Hee-Jin Kim, Seung Heon Lee
Received December 27, 2023   Accepted April 26, 2024   Published online May 3, 2024   
DOI: https://doi.org/10.4046/trd.2023.0197    [Epub ahead of print]
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Exploring the Association of Bacterial Coinfections with Clinical Characteristics of Patients with Nontuberculous Mycobacterial Pulmonary Disease
Seong Mi Moon, Hyunkyu Cho, Beomsu Shin
Received January 7, 2024   Accepted April 24, 2024   Published online April 30, 2024   
DOI: https://doi.org/10.4046/trd.2024.0003    [Epub ahead of print]
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Nonpharmacological Treatment for Nontuberculous Mycobacterial Pulmonary Disease
Hyung-Jun Kim
Received March 8, 2024   Accepted April 24, 2024   Published online April 25, 2024   
DOI: https://doi.org/10.4046/trd.2024.0033    [Epub ahead of print]
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Original Articles
Inappropriate Peak Inspiratory Flow Rate in the Patients with Stable Chronic Obstructive Pulmonary Disease in Korea
Seong Hwan Youn, Hyun Jung Kim, Jae Seok Park, Sun Hyo Park, Yong Shik Kwon, Mi-Ae Kim
Received December 20, 2023   Accepted April 23, 2024   Published online April 25, 2024   
DOI: https://doi.org/10.4046/trd.2023.0195    [Epub ahead of print]
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Letter to the Editor
Public-Private Partnership for Tuberculosis Care and Prevention in Korea
Jinsoo Min, Yoolwon Jeong
Received February 19, 2024   Accepted April 7, 2024   Published online April 9, 2024   
DOI: https://doi.org/10.4046/trd.2024.0022    [Epub ahead of print]
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