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Effects of Antioxidant on Oxidative Stress and Autophagy in Bronchial Epithelial Cells Exposed to Particulate Matter and Cigarette Smoke Extract |
Jung Hur, Chin Kook Rhee, Yong Suk Jo |
Tuberc Respir Dis. 2022;85(3):237-248. Published online March 23, 2022 DOI: https://doi.org/10.4046/trd.2021.0152 |
Effects of Antioxidant on Oxidative Stress and Autophagy in Bronchial Epithelial Cells Exposed to Particulate Matter and Cigarette Smoke Extract Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract Thymoquinone (Tq) protects necroptosis induced by autophagy/mitophagy‐dependent oxidative stress in human bronchial epithelial cells exposed to cigarette smoke extract (CSE) Angiopoietin-like 4 knockdown attenuates cigarette smoke extract–induced oxidative stress and apoptosis in lung bronchial epithelial cells by inhibiting NADPH oxidase ANDROGRAPHOLIDE SIMULTANEOUSLY AUGMENTS NRF2 ANTIOXIDANT DEFENSE AND FACILITATE AUTOPHAGIC FLUX BLOCKADE IN CIGARETTE SMOKE‐EXPOSED HUMAN BRONCHIAL EPITHELIAL CELLS Cigarette smoke extract-mediated FABP4 upregulation suppresses viability and induces apoptosis, inflammation and oxidative stress of bronchial epithelial cells by activating p38 MAPK/MK2 signaling pathway Oxidative stress responses in human bronchial epithelial cells exposed to cigarette smoke and vapor from tobacco- and nicotine-containing products Sappanone A inhibits oxidative stress, inflammation and apoptosis in cigarette smoke-induced human bronchial epithelial cells through regulating Nrf2/HO-1 and TLR4/NF-κB signaling pathways DUAL BRONCHODILATOR SUPPRESSES CIGARETTE SMOKE EXTRACT‐INDUCED AUTOPHAGIC CELL DEATH IN HUMAN BRONCHIAL EPITHELIAL CELLS A proof of concept study to model a tiered oxidative stress response in lung epithelial cells exposed to cigarette smoke aqueous extract |