Tuberc Respir Dis > Volume 57(6); 2004 > Article
Tuberculosis and Respiratory Diseases 2004;57(6):573-578.
DOI:    Published online December 1, 2004.
A Case of Idiopathic Hypereosinophilic Syndrome Complicated with Pulmonary Thromboembolism and Disseminated Intravascular Coagulation.
Jong Sung Lee, Hyun Kyung Lee, Sung Soon Lee, Jae Yong Jin, Young Min Lee, Hyuk Pyo Lee, Joo In Kim, Bon Il Ku, Soo Jeon Choi, Ho Kee Yum
Department of Internal Medicine, and Thoracic Surgery Seoul Paik Hospital, Inje University, Korea.
The idiopathic hypereosinophilic syndrome (HES) comprises a heterogeneous group of disorders with unknown pathogenesis characterized by persistent peripheral blood and bone marrow eosinophilia. And the eosinophil infiltrates of multiple organs in HES lead to severe organ dysfunction. The disseminated intravascular coagulation (DIC) is a rare complication of HES. We have experienced a case of HES complicated with DIC and pulmonary thromboembolism. After intravenous injection of methylprednisone, blood eosinophil count was normalized but DIC was persisted. With cortico steroid and cyclosporine therapy, the disease activity was favorably remitted.
Key Words: Idiopathic hypereosinophilic syndrome, DIC, cyclosporin, thromboembolism

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