Tuberc Respir Dis > Volume 63(3); 2007 > Article
Tuberculosis and Respiratory Diseases 2007;63(3):261-267.
DOI: https://doi.org/10.4046/trd.2007.63.3.261    Published online September 1, 2007.
Diagnostic Accuracy and Safety of Medical Thoracoscopy.
Jung Kyung Yang, Jung Ho Lee, Mi Hye Kwon, Ji Hyun Jeong, Go Eun Lee, Hyun Min Cho, Young Jin Kim, Sung Mee Jung, Eu Gene Choi, Ji Woong Son, Moon Jun Na
1Department of Internal Medicine, College of Medicine, Konyang University, Daejeon, Korea. mjna@ns.kyuh.co.kr
2Department of Thoracic & Cardiovascular Surgery, College of Medicine, Konyang University, Daejeon, Korea.
3Department of Anesthesiology, College of Medicine, Konyang University, Daejeon, Korea.
Abstract
BACKGROUND
The causes of the pleural effusion are remained unclear in a the substantial number of patients with exudative effusions determined by an examination of the fluid obtained via thoracentesis. Among the various tools for diagnosing exudative pleural effusions, thoracoscopy has a high diagnostic yield for cancer and tuberculosis. Medical thoracoscopy can also be carried out under local anesthesia with mild sedation. The aim of this study was to determine diagnostic accuracy and safety of medical thoracoscopy. METHODS: Twenty-five patients with exudative pleural effusions of an unknown cause underwent medical thoracoscopy between October 2005 and September 2006 in Konyang University Hospital. The clinical data such as age, gender, preoperative pulmonary function, amounts of pleural effusion on lateral decubitus radiography were collected. The vital signs were recorded, and arterial blood gas analyses were performed five times during medical thoracoscopy in order to evaluate the cardiopulmonary status and acid-base changes. RESULTS: The mean age of the patients was 56.8 years (range 22-79). The mean depth of the effusion on lateral decubitus radiography (LDR) was 27.49 mm. The medical thoracoscopic pleural biopsy was diagnostic in 24 patients (96.0%), with a diagnosis of tuberculosis pleurisy in 9 patients (36%), malignant effusions in 8 patients (32%), and parapneumonic effusions in 7 patients (28%). Medical thoracoscopy failed to confirm the cause of the pleural effusion in one patient, who was diagnosed with tuberculosis by a pericardial biopsy. There were no significant changes in blood pressure, heart rate, acid-base and no major complications in all cases during medical thoracoscopy (p>0.05). CONCLUSIONS: Medical thoracoscopy is a safe method for patients with unknown pleural effusions with a relatively high diagnostic accuracy.
Key Words: Accuracy, Biopsy, Diagnosis, Medical thoracoscopy, Pleural effusion, Safety


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