Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer.

Lee, Chang Youl; Chung, Jae Hee; Chang, Yoon Soo; Kim, Se Kyu; Kim, Hyung Jung; Chang, Joon; Kim, Sung Kyu; Ahn, Chul Min

doi:2007.62.4.284

Tuberc Respir Dis > Volume 62(4); 2007 > Article

Original Article

Tuberculosis and Respiratory Diseases 2007;62(4):284-289.
DOI: https://doi.org/10.4046/trd.2007.62.4.284 Published online April 1, 2007.

Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer.

Chang Youl Lee, Jae Hee Chung, Yoon Soo Chang, Se Kyu Kim, Hyung Jung Kim, Joon Chang, Sung Kyu Kim, Chul Min Ahn

¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. ahnswine@naver.com
²THuman Barrier Research Center, Yonsei University College of Medicine, Seoul, Korea.

Abstract

BACKGROUND
To define the clinical features of patients with lung and upper aerodigestive tract cancer through a review of the histopathology, clinical features and follow-up results. METHODS: Patients with lung and upper aerodigestive tract cancer who were diagnosed in Young dong Severance Hospital from 1992 to 2005, were retrospectively reviewed. The clinical data, radiologic findings, pathologic findings, treatment modalities were evaluated. Result: There was a total of 20 patients with aerodigestive tract cancer who were diagnosed with lung cancer over a 13 years period. The mean age was 58.45 +/-15.09 years and 19 cases were male. There were 14 smokers with an average pack year of 46 years. Twelve patients had aerodigestive tract cancer and later developed lung cancer, and 5 lung cancer patients were later diagnosed with aerodigestive tract cancer. CONCLUSION: These results suggest that cancers of the aerodigestive tract and lung can arise as either dependent or independent events and most aerodigestive tract cancer patients who developed lung cancer are not treated properly. Therefore, regular low dose chest CT with close suspicion is needed to properly manage upper aerodigestive tract cancer patients.

Key Words: Aerodigestive tract cancer, Lung cancer, Clinical feature