A Case of Goodpasture's Syndrome Combined with Crohn's Disease.

Kim, Ji Yon; Bae, Jun Yong; Jung, Eun Jung; Kim, Yang Ki; Lee, Young Mok; Kim, Ki Up; Uh, Soo taek; Hwang, Jung Hwa; Jin, So Young; Lee, Dong Wha

doi:2006.61.4.384

Tuberc Respir Dis > Volume 61(4); 2006 > Article

Case Report

Tuberculosis and Respiratory Diseases 2006;61(4):384-388.
DOI: https://doi.org/10.4046/trd.2006.61.4.384 Published online October 1, 2006.

A Case of Goodpasture's Syndrome Combined with Crohn's Disease.

Ji Yon Kim, Jun Yong Bae, Eun Jung Jung, Yang Ki Kim, Young Mok Lee, Ki Up Kim, Soo taek Uh, Jung Hwa Hwang, So Young Jin, Dong Wha Lee

¹Division of Respiratory & Allergy Medicine, Department of Internal Medicine, Soonchunhyang University, School of Medicine, Seoul, Korea. uhs@hosp.sch.ac.kr
²Department of Radiology, Soonchunhyang University, School of Medicine, Seoul, Korea.
³Department of Clinical Pathology, Soonchunhyang University, School of Medicine, Seoul, Korea.

Abstract

A 29-year-old male patient was admitted due to his general weakness and poor oral intake for several months. He was diagnosed as having Crohn disease 16 years ago and total colectomy was performed 10 years ago. On the 3rd day after admission, gross hematuria and sudden hemoptysis combined with diffuse infiltration were noted on chest X-ray. His symptoms and the diffusely increased lung opacities improved with administering high-dose steroid therapy. Later, anti-GBM antibody was found to be positive on the laboratory findings. We report here on a rare case of Goodpsture syndrome combined with prolonged Crohn disease along with a review of literature.

Key Words: Goodpsture syndrome, Crohn disease, anti-GBM antibody