Tuberc Respir Dis > Volume 61(3); 2006 > Article
Tuberculosis and Respiratory Diseases 2006;61(3):218-226.
DOI: https://doi.org/10.4046/trd.2006.61.3.218    Published online September 1, 2006.
Selection of Reference Equations for Lung Volumes and Diffusing Capacity in Korea.
Eun Hee Song, Yeon Mok Oh, Sang Bum Hong, Tae Sun Shim, Chae Man Lim, Sang Do Lee, Youn Suck Koh, Woo Sung Kim, Dong Soon Kim, Won Dong Kim, Tae Hyung Kim
1Department of Internal Medicine and Clinical Research Center for Chronic Obstructive Airway Disease, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
2Division of Pulmonology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea. drterry@hanyang.ac.kr
Abstract
BACKGROUND
The lung volume and diffusing capacity are influenced by ethnicity. However, there are no equations for predicting the normal lung volume in the adult Korean population, and there is only one equation for diffusing capacity. The aim of this study is to select the most suitable reference equation for the Korean population. METHOD: 30 men and 33 women at Hanyang University Guri Hospital, and 27 men and 34 women at Asan Medical Center in healthy nonsmoking adults were enrolled in this study. The subject's age, gender, height, weight, lung volume by plethysmography, and diffusing capacity by a single breathing method were obtained. The most suitable equation with the lowest sum of residuals between the observed and predicted values for lung volume and diffusing capacity was selected. RESULT: At Hanyang University Guri Hospital, the equations with the lowest sum of residuals in the total lung capacity were ECSC's equation in males (sum of residual: 0.04 L) and Crapo/Morris's equation (-1.04) in women. At the Asan Medical Center, the equations with the lowest sum of residuals in the total lung capacity were Goldman/Becklake's equation in males (sum of residual: -2.35) and the ECSC's equation -4.49) in women. The equations with the lowest sum of residuals in the Diffusing capacity were Roca's equation in males (sum of residual: -13.66 ml/min/mmHg) and Park's in women (25.08) in Hanyang University Guri hospital and Park's equation in all cases in the Asan Medical Center (male: -1.65 , female: -6.46). CONCLUSIONS: Until a reference equstion can be made for healthy Koreans by sampling, ECSC's equation can be used for estimating the lung volume and Park's can be used for estimating the diffusing capacity.
Key Words: Reference equation, Lung volume, Diffusing capacity


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