Insidious Onset of Amiodarone Pulmonary Toxicity Presented with Hemoptysis.

Kim, Hearn Kook; Jung, Bock Hyun; Han, Kun Hee; Hwang, Jung Won; Cho, Young Ju; Park, Yong Jin; Jung, Hyoung Jung; Kim, Mi Hye; Ryu, Dae Sik; Kang, Gil Hyun

doi:2005.59.4.413

Tuberc Respir Dis > Volume 59(4); 2005 > Article

Case Report

Tuberculosis and Respiratory Diseases 2005;59(4):413-417.
DOI: https://doi.org/10.4046/trd.2005.59.4.413 Published online October 1, 2005.

Insidious Onset of Amiodarone Pulmonary Toxicity Presented with Hemoptysis.

Hearn Kook Kim, Bock Hyun Jung, Kun Hee Han, Jung Won Hwang, Young Ju Cho, Yong Jin Park, Hyoung Jung Jung, Mi Hye Kim, Dae Sik Ryu, Gil Hyun Kang

¹Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital, Gangneung, Korea. jbh@gnah.co.kr
²Department of Diagnostic Radiology, University of Ulsan, Gangneung Asan Hospital, Gangneung, Korea.
³Department of Diagnostic Pathology University of Ulsan, Gangneung Asan Hospital, Gangneung, Korea.

Abstract

Amiodarone is widely used to control fatal arrhythmia. However, amiodarone therapy is associated with a relatively high incidence of pulmonary toxicity, up to 5 to 10%. Typical symptoms are nonspecific and often manifest as nonproductive cough, dyspnea and interstitial infiltrates in patients with acute pneumonitis or chronic fibrosis. However, hemoptysis is a very rare symptom of amiodarone pulmonary toxicity. We report a case of amiodarone pulmonary toxicity, who presented with hemoptysis and was successfully treated with the cessation of amiodarone, with review of the relevant literature.

Key Words: Amiodarone pulmonary toxicity, Hemoptysis, Acute pneumonitis