Tuberc Respir Dis > Volume 57(3); 2004 > Article
Tuberculosis and Respiratory Diseases 2004;57(3):278-283.
DOI: https://doi.org/10.4046/trd.2004.57.3.278    Published online September 1, 2004.
A Case of Primary Leiomyosarcoma with Prominent Osteoclast-like Giant Cell of Lung with Cardiac Invasion.
Ki Ryong Song, Yongseon Cho, Sung Kyun Sin, Ho Seok Jeon, Woo Jin Hyun, Yang Deok Lee, Min soo Han, Ji Young Rho, Kyung Hee Kim
1Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea. casimirus@chollian.net
2Department of Diagnostic Radiology, Eulji University Hospital, Daejeon, Korea.
3Department of Pathology, Eulji University Hospital, Daejeon, Korea.
Abstract
The incidence of a pulmonary leiomyosarcoma as a primary lung tumor is quite rare. We report a case of primary leiomyosarcoma with a cardiac invasion in a 76 year old man. He was admitted due to left anterior chest wall pain for one month. Chest computed tomography showed a 9x8x10cm sized , large round mass in the left upper and lower lobes, and an amorphous low density lesion within the left atrium. Chest magnetic resonance imaging showed a large round mass in the left upper and lower lobes with growth into the left atrium. A diagnosis of leiomyosarcoma with prominent osteoclast-like giant cells was made based on the microscopic and immunohistochemical findings of a permanent specimen by explothoracotomy. The pathologic features of the tumor showed round mononuclear hyperchromatic cells and multinucleated giant cells that resembled osteoclasts. The immunohistochemical staining showed that the giant cells are positive for CD68 but negative for the muscle markers while the round cells were positive for the muscle marker. The patient refused further treatment and died after two months.
Key Words: Leiomyosarcoma, Lung, Cardiac invasion, Prominent osteoclast-like giant cells


ABOUT
ARTICLE & TOPICS
Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES
FOR CONTRIBUTORS
Editorial Office
101-605, 58, Banpo-daero, Seocho-gu (Seocho-dong, Seocho Art-Xi), Seoul 06652, Korea
Tel: +82-2-575-3825, +82-2-576-5347    Fax: +82-2-572-6683    E-mail: katrdsubmit@lungkorea.org                

Copyright © 2024 by The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.

Developed in M2PI

Close layer
prev next