A Case of Isoniazid Induced Acute Pancreatitis.

Chung, Byung Ha; Nam, Hae Seong; Kwon, Jung Hyun; Im, So Hi; Park, Sun Hee; Kim, Jin Woo; Kim, Seung Joon; Lee, Sook Young; Kim, Young Kyoon; Park, Sung Hak

doi:2004.56.4.411

Tuberc Respir Dis > Volume 56(4); 2004 > Article

Case Report

Tuberculosis and Respiratory Diseases 2004;56(4):411-414.
DOI: https://doi.org/10.4046/trd.2004.56.4.411 Published online April 1, 2004.

A Case of Isoniazid Induced Acute Pancreatitis.

Byung Ha Chung, Hae Seong Nam, Jung Hyun Kwon, So Hi Im, Sun Hee Park, Jin Woo Kim, Seung Joon Kim, Sook Young Lee, Young Kyoon Kim, Sung Hak Park

Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea. youngkim@catholic.ac.kr

Abstract

Isoniazid is a first-line drug in the treatment of tuberculosis. A variety of adverse reactions of isoniazid have been reported. These include hepatitis, peripheral neuropathy, skin rashes, neurologic disturbances and hematologic alterations. Among these, acute pancreatitis due to isoniazid is very rare. We report a case of acute pancreatitis due to isoniazid confirmed by rechallenge test with review of some literatures.

Key Words: Tuberculosis, Isoniazid, Rifampicin, Acute pancreatitis