Allergic Bronchopulmonary Aspergillosis Associated with Aspergilloma.

Ryu, Jeon Su; Baik, Jae Joong; Kim, Do Kyun; Kim, Young Jin; Eom, Woo Seob; Cho, Jea Hyun

doi:2004.56.3.302

Tuberc Respir Dis > Volume 56(3); 2004 > Article

Case Report

Tuberculosis and Respiratory Diseases 2004;56(3):302-307.
DOI: https://doi.org/10.4046/trd.2004.56.3.302 Published online March 1, 2004.

Allergic Bronchopulmonary Aspergillosis Associated with Aspergilloma.

Jeon Su Ryu, Jae Joong Baik, Do Kyun Kim, Young Jin Kim, Woo Seob Eom, Jea Hyun Cho

Department of Internal Medicine, National Medical Center, Korea. typist@hanmail.net

Abstract

Aspergilloma and Allergic Bronchopulmonary Aspergillosis(ABPA) are different types of the pulmonary aspergillosis spectrum of diseases. ABPA is an inflammatory disease that causes hypersensitivity to Aspergillus spores growing in the bronchi, which is characterized by asthma, recurrent pulmonary infiltrations or mucoid impaction, eosinophilia and central bronchiectasis. Aspergilloma is a simple colonization of fungus within a cavitary lung lesion, but these diseases rarely coexist. A case of ABPA, coexistent with Aspergilloma, was experienced in a 31 year-old female. The diagnosis was confirmed by the immediate cutaneous reactivity to Aspergillus fumigatus, elevated total IgE antibodies, peripheral eosinophilia, bronchiectasis, growth of Aspergillus species in a sputum culture and radiographic infiltration. Treatment, with prednisone and itraconazole, led to improvement of the respiratory symptoms, reduction of the cavitary lesion and in the total serum IgE level.

Key Words: Allergic bronchopulmonary aspergillosis, Aspergilloma