Clinical usefulness of Clinical Pulmonary Infection Score of ICU Patients with Sputum Culture positive for Multi-drug resistant Acinetobacter baumannii. |
Ji Hyun Lee, Seok Cheol Cheon, Sun Hye Jung, Lae Hyun Phyun, Moon Zu Jang, Stephen Yonggu Lee, Sung Kwan Hong, Seong Geun Hong, Ji Hyun Lee, Sang Bum Hong |
1Department of Internal Medicine, Bundang CHA Hospital, College of Medicine, Pochon CHA University, Korea. sbhong@cha.ac.kr 2Department of Laboratory Medicine, Bundang CHA Hospital, College of Medicine, Pochon CHA University, Korea. |
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Abstract |
BACKGROUND The hospital-acquired pneumonia is the most common nosocomial infection. Recently, the Acinetobacter baummannii infections are rapidly increasing, especially the frequency of Multi-drug resistant A. baumannii. Therefore we assessed clinical features and prognosis of patients in the ICU with Multi-drug resistant A. baumannii from the sputum culture using the Clinical Pulmonary Infection Score(CPIS). METHODS: The medical records of 43 patients with Multi-drug resistant A. baumannii from sputum culture who were suspected had clinically pneumonia and admitted to the ICU from January 2000 to July 2002 were retrospectively analyzed. RESULT: 19 patients were CPIS greater than 6 and 24 patients were CPIS less than or equal to 6. Mean age for the former was 71+/-11 years old, and the latter was 61+/-19 years old. The mean APACHE II score on admission and on sputum study was not different between two groups(17.4+/-5.7 vs 18.5+/-6.1, p=0.553, 20+/-6 vs 17+/-8, p=0.078). But the mortality rate was 73.7% for the former, and 16.7% for the latter(p<0.001). CONCLUSION: In ICU patients who had clinically suspected pneumonia with sputum culture positive for Multi-drug resistant A. baumannii, the mortality was significantly higher if CPIS was greater than 6. |
Key Words:
Multi-drug resistant Acinetobacter baumannii, Hospital acquired pneumonia, Clinical Pulmonary Infection Score (CPIS) |
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