Tuberc Respir Dis > Volume 55(6); 2003 > Article
Tuberculosis and Respiratory Diseases 2003;55(6):579-588.
DOI: https://doi.org/10.4046/trd.2003.55.6.579    Published online December 1, 2003.
Clinical usefulness of Clinical Pulmonary Infection Score of ICU Patients with Sputum Culture positive for Multi-drug resistant Acinetobacter baumannii.
Ji Hyun Lee, Seok Cheol Cheon, Sun Hye Jung, Lae Hyun Phyun, Moon Zu Jang, Stephen Yonggu Lee, Sung Kwan Hong, Seong Geun Hong, Ji Hyun Lee, Sang Bum Hong
1Department of Internal Medicine, Bundang CHA Hospital, College of Medicine, Pochon CHA University, Korea. sbhong@cha.ac.kr
2Department of Laboratory Medicine, Bundang CHA Hospital, College of Medicine, Pochon CHA University, Korea.
Abstract
BACKGROUND
The hospital-acquired pneumonia is the most common nosocomial infection. Recently, the Acinetobacter baummannii infections are rapidly increasing, especially the frequency of Multi-drug resistant A. baumannii. Therefore we assessed clinical features and prognosis of patients in the ICU with Multi-drug resistant A. baumannii from the sputum culture using the Clinical Pulmonary Infection Score(CPIS). METHODS: The medical records of 43 patients with Multi-drug resistant A. baumannii from sputum culture who were suspected had clinically pneumonia and admitted to the ICU from January 2000 to July 2002 were retrospectively analyzed. RESULT: 19 patients were CPIS greater than 6 and 24 patients were CPIS less than or equal to 6. Mean age for the former was 71+/-11 years old, and the latter was 61+/-19 years old. The mean APACHE II score on admission and on sputum study was not different between two groups(17.4+/-5.7 vs 18.5+/-6.1, p=0.553, 20+/-6 vs 17+/-8, p=0.078). But the mortality rate was 73.7% for the former, and 16.7% for the latter(p<0.001). CONCLUSION: In ICU patients who had clinically suspected pneumonia with sputum culture positive for Multi-drug resistant A. baumannii, the mortality was significantly higher if CPIS was greater than 6.
Key Words: Multi-drug resistant Acinetobacter baumannii, Hospital acquired pneumonia, Clinical Pulmonary Infection Score (CPIS)


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