A Case of Primary Malignant Fibrous Histiocytoma of the Diaphragm.

Shim, Jaejun; Cho, Yongseon; Kim, Hyun Sook; Choi, Hye Sook; Choi, Cheon Woong; Yoo, Jee Hong; Kang, Hong Mo; Yang, Moon Ho

doi:2003.54.6.645

Tuberc Respir Dis > Volume 54(6); 2003 > Article

Case Report

Tuberculosis and Respiratory Diseases 2003;54(6):645-650.
DOI: https://doi.org/10.4046/trd.2003.54.6.645 Published online June 1, 2003.

A Case of Primary Malignant Fibrous Histiocytoma of the Diaphragm.

Jaejun Shim, Yongseon Cho, Hyun Sook Kim, Hye Sook Choi, Cheon Woong Choi, Jee Hong Yoo, Hong Mo Kang, Moon Ho Yang

¹Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, Korea. casimirus@chollian.net
²Department of Internal Medicine, School of Medicine, Eulji University, Korea.
³Department of Pathology School of Medicine, Kyung Hee University, Seoul, Korea.

Abstract

A malignant fibrous histiocytoma (MFH) is a major subset of soft tissue sarcomas, which occurs principally on the extremities or in the retroperitoneum, as well as on the head and neck of elderly patient. However, it is an extremely rare event when a MFH occurs primarily in the diaphragm of a young people. A 25-year-old woman visited our hospital complaining of right chest pain. The chest X-ray showed a diaphragmatic mass. An exploratory thoracotomic biopsy revealed a primary MFH of the diaphragm. The patient was treated with combined chemotherapy consisting of ifosfamide and doxorubicin. A partial response was seen after 6 cycles of chemotherapy. However, she died of brain metastasis 12 months after the diagnosis.

Key Words: Fibrous Histiocytoma, Diaphragm