A Case of Metastatic Non-small Cell Lung Cancer Presenting with Numb Chin Syndrome.

Park, Won Chul; Kim, Kyung Duk; Shin, Sang Hyo; Lim, Jae Min; Bae, Sung Jin; Im, Joo Hyuk; Lim, Chae Man; Lee, Sang Do; Kim, Dong Soon; Kim, Won Dong; Kim, Woo Sung

doi:2002.53.1.46

Tuberc Respir Dis > Volume 53(1); 2002 > Article

Case Report

Tuberculosis and Respiratory Diseases 2002;53(1):46-51.
DOI: https://doi.org/10.4046/trd.2002.53.1.46 Published online July 1, 2002.

A Case of Metastatic Non-small Cell Lung Cancer Presenting with Numb Chin Syndrome.

Won Chul Park, Kyung Duk Kim, Sang Hyo Shin, Jae Min Lim, Sung Jin Bae, Joo Hyuk Im, Chae Man Lim, Sang Do Lee, Dong Soon Kim, Won Dong Kim, Woo Sung Kim

¹Department of Internal medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. wskim2@amc.seoul.kr
²Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Numb chin syndrome is a rare clinical manifestation, characterized by focal sensory loss and paresthesia of the chin. It is more often associated with cancer than with benign disorders, and can be the first manifestation of a cancer. A 60-year-old man presented with focal numbness of right chin and gingiva for 10 days. Chest computed tomography showed a 3 cm sized mass on the distal left main-stem bronchus. Squamous cell carcinoma was diagnosed on bronchoscopic biopsy. However, bony metastasis of mandible was not evident on reontgenogram, CT scan, bone scintigram and positron emission tomography. Despite the chemotherapy with three cycles of paclitaxel and cisplatinum, the cancer was progressed and pain on the right chin was developed 4 months .later. Bone scintigram showed multiple bony metastasis including mandible. Here we report this case with a brief review of the appropriate literature.

Key Words: Numb chin syndrome, Non-small cell lung cancer