A Case of Membranous Glomerulonephritis Associated with Small Cell Lung Cancer Being Complete Remmission with Chemotherapy.

Pack, Jong Hae; Park, Ji Young; Yu, Sung Keun; Park, Hye Jung; Shin, Kyeong Cheol; chung, Jin Hong; Lee, Kwan Ho

doi:2002.52.6.633

Tuberc Respir Dis > Volume 52(6); 2002 > Article

Case Report

Tuberculosis and Respiratory Diseases 2002;52(6):633-639.
DOI: https://doi.org/10.4046/trd.2002.52.6.633 Published online June 1, 2002.

A Case of Membranous Glomerulonephritis Associated with Small Cell Lung Cancer Being Complete Remmission with Chemotherapy.

Jong Hae Pack, Ji Young Park, Sung Keun Yu, Hye Jung Park, Kyeong Cheol Shin, Jin Hong chung, Kwan Ho Lee

Department of Internal Medicine, College of Medicine,Yeungnam University, Daegu, Korea. ghlee@med.yu.ac.kr

Abstract

Paraneoplastic nephrotic syndrome can be diagnosed from its clinical and immunological features. The development of several types of glomerular injury in patients with cancer have been recognized, and are considered as paraneoplastic syndrome. Most prominent are the occurrence of membranous glomerulonephritis in patients with carcinomas. We report a case of a 60-year-old-man with small cell lung cancer presenting as nephrotic syndrome. A renal biopsy revealed membranous glomerulonephritis. Six lots of chemotherapy were administerd, which led to a complete tumor response with total resolution of the nephrotic syndrome following treatment.

Key Words: Small cell lung cancer, Membranous glomerulonephritis