A Case Pulmonary Epithelioid Hemangioendothelioma that Underwent Unusual Malignant Course.

Yoon, Hyoung Kyu; Kim, Tae Yeon; Jung, Jung Im; Lee, Kyo Young; Moon, Hwa Sik; Park, Sung Hak; Song, Jeong Sup

doi:2001.51.5.466

Tuberc Respir Dis > Volume 51(5); 2001 > Article

Case Report

Tuberculosis and Respiratory Diseases 2001;51(5):466-473.
DOI: https://doi.org/10.4046/trd.2001.51.5.466 Published online November 1, 2001.

A Case Pulmonary Epithelioid Hemangioendothelioma that Underwent Unusual Malignant Course.

Hyoung Kyu Yoon, Tae Yeon Kim, Jung Im Jung, Kyo Young Lee, Hwa Sik Moon, Sung Hak Park, Jeong Sup Song

Abstract

Pulmonary epithelioid hemangioendothelioma (PEH), originally termed an intravacular bronchioloalveolar tumor, is a rare pulmonary neoplasm with a vascular origin and slow rate of malignancy. It affects various organs such as the liver, the central nervous system, lung, etc. Clinically, pulmonary epithelioid hemangioendothelioma has been considered to be a borderline malignancy, a generally indolent and nonaggressive tumor that displaes the pulomonary parenchyma over a number of years by slowly enlarging the tumor nodule. The clinical course of PEH is known to be usually benign. Here we report an unusual case of PEH that was highly malignant and was eventually fatal. The PEH was confirmed by microscopic analysis and hmmunohistochemical staining of CD31+(a membrane receptor and a sensitive and specific marker for vascular lesions) from an open lung biopsy specimen.

Key Words: Pulmonary epithelioid hemangioendothelioma, Malignant course