A Case of the Membranous Glomerulonephritis Associated with Squamous Cell Lung Cancer.

Cho, You Lee; Seo, Young Jin; Kim, Moo Gon; Lee, Jhun Yeob; Jung, Seung Hie; Ryoo, Hun Mo; Yeun, Hyen Dae; Lee, In Hee; Ahn, Ki Sung; Sin, Tae Lim; Hyun, Dae Sung; Lee, Sang Chae; Cho, Chang Ho

doi:2001.51.2.178

Tuberc Respir Dis > Volume 51(2); 2001 > Article

Case Report

Tuberculosis and Respiratory Diseases 2001;51(2):178-183.
DOI: https://doi.org/10.4046/trd.2001.51.2.178 Published online August 1, 2001.

A Case of the Membranous Glomerulonephritis Associated with Squamous Cell Lung Cancer.

You Lee Cho, Young Jin Seo, Moo Gon Kim, Jhun Yeob Lee, Seung Hie Jung, Hun Mo Ryoo, Hyen Dae Yeun, In Hee Lee, Ki Sung Ahn, Tae Lim Sin, Dae Sung Hyun, Sang Chae Lee, Chang Ho Cho

Abstract

The nephrotic syndrome that occurs in the absence of renal vein thrombosis, amyloidosis, neoplastic infiltration of the kidneys is an unusual but a well recognized paraneoplastic syndrome. The most frequently reported neoplasms associated with nephrotic syndrome are Hodgkin's disease and various carcinomas. The most common renal lesions are membranous glomerulonephritis(MGN) associated with carcinomas and minimal change lesions associated with Hodgkin's disease. Approximately 40% to 45% of patients clinically manifest the MGN symptoms prior to the diagnosis of the tumor, 40% simultaneously with the tumor and the remaining 15% to 20% following the tumor. Therefore, evaluating the underlying malignancy in patients with MGN is important. Here we report a patient with squamous cell lung cancer, which was detected 12 months after a MGN had been diagnosed, with a review of the relevant literature.

Key Words: Squamous cell lung cancer, Nephrotic syndrome, Menbranous glomerulonephritis(MGN)