A Case of Nonspecific Interstitial Pneumonia with Clinical Course of Rapid Aggravation.

Yoo, Byung Hyun; Suhr, Ji Won; Yoon, Hee Jeoung; Baek, Jong Tae; Lee, Seung Hoon; Paik, Chang Nyol; Lee, Ji Eun; Kim, Seung Joon; Park, Sung Hak; Lee, Eun Hee

doi:2001.51.1.59

Tuberc Respir Dis > Volume 51(1); 2001 > Article

Case Report

Tuberculosis and Respiratory Diseases 2001;51(1):59-64.
DOI: https://doi.org/10.4046/trd.2001.51.1.59 Published online July 1, 2001.

A Case of Nonspecific Interstitial Pneumonia with Clinical Course of Rapid Aggravation.

Byung Hyun Yoo, Ji Won Suhr, Hee Jeoung Yoon, Jong Tae Baek, Seung Hoon Lee, Chang Nyol Paik, Ji Eun Lee, Seung Joon Kim, Sung Hak Park, Eun Hee Lee

Abstract

Nonspecific interstitial pneumonia (NSIP) was first described as a new category of idiopathic interstitial pneumonia in 1994. This is a disease with a more insidious onset and has a chronic course. The histological findings are unusual for other idiopathic interstitial pneumonia cases (usual interstitial pneumonia, diffuse interstitial pneumonia, and acute interstitial pneumonia). In contrast to NSIP, acute interstitial pneumonia (AIP) has an acute onset and a fulminant course with the rapid development of respiratory failure. A pathological examination demonstrated characteristic diffuse interstitial fibrosis, hyaline membranes, thrombi, and architectural derangement. Here we report a 48-year-old woman who was diagnosed pathologically NSIP, but with a rapid progressive course similar to AIP.

Key Words: Non Specific Interstitial Pneumonia (NSIP), Acute Interstitial Pneumonia (AIP), Idiopathic Pulmonary Fibrosis (IPF)