Incidentally Founded Biphasic Pulmonary Blastoma.

Kim, Nam Hoon; Keum, Dong oon; Kim, Joo Heon; Park, Mee Ja

doi:2001.50.5.641

Tuberc Respir Dis > Volume 50(5); 2001 > Article

Case Report

Tuberculosis and Respiratory Diseases 2001;50(5):641-644.
DOI: https://doi.org/10.4046/trd.2001.50.5.641 Published online May 1, 2001.

Incidentally Founded Biphasic Pulmonary Blastoma.

Nam Hoon Kim, Dong oon Keum, Joo Heon Kim, Mee Ja Park

Abstract

Pulmonary blastoma is a family of tumors in which the glands or mesenchyme composing the neoplasm are primitive or embryonic in appearance. There are three subtypes, which include well differentiated fetal adenocarcinoma (pulmonary endodermal tumor), biphasic pulmonary blastoma, and cystic and pleuropulmonary blastomas in children. Among them, biphasic pulmonary blastoma is a primary malignancy of the lung originating from multipotential pulmonary blastema including both the malignant fetal epithelial and mesenchymal components. These make up 0.25 to 0.5 percent of all primary malignant lung tumors. This tumor is usually symptomatic and appears as a large, solitary peripheral mass, with a tendency to favor the upper lobe. Here we report a case where small sized asymptomatic peripheral lung mass was diagnosed as a biphasic pulmonary blastoma, prior to the operation, A subsequent percutaneous needle biopsy was performed, which revealed features of a large cell neuroendocirne tumor. In addition, a review of the relevant literature is provided.

Key Words: Pulmonary blastoma, biphasic