A Case of chronic necrotizing pulmonary aspergillosis with pulmonary artery aneurysm.

Kim, Hwi Jong; Chung, Hyo Young; Kim, Soo Hee; Yun, Ji Chul; Lee, Jong Deog; Hwang, Young Sil

doi:2000.49.1.105

Tuberc Respir Dis > Volume 49(1); 2000 > Article

Case Report

Tuberculosis and Respiratory Diseases 2000;49(1):105-110.
DOI: https://doi.org/10.4046/trd.2000.49.1.105 Published online July 1, 2000.

A Case of chronic necrotizing pulmonary aspergillosis with pulmonary artery aneurysm.

Hwi Jong Kim, Hyo Young Chung, Soo Hee Kim, Ji Chul Yun, Jong Deog Lee, Young Sil Hwang

Abstract

Pulmonary aspergillosis is classified as a saprophytic, allergic, and invasive disease. Chronic necrotizing pulmonary aspergillosis is categorized as an invasive pulmonary aspergillosis. Most invasive pulmonary aspergillosis have acute and toxic clinical features but chronic necrotizing pulmonary aspergillosis is characterized by a sub-acute infection, most commonly seen in patients with altered local defense system from preexisting pulmonary disease of in mild immunocompromised patients. Pulmonary artery aneurysm due to this infection is termed as a mycotic aneurysm, etiology of which are tuberculosis, syphilis, bacteria and fungus. We report a case chronic necrotizing pulmonary aspergillosis complicating pulmonary aneurysm is a 62 year-old man who was presented with cough, sputum, and fever. Chest radiographs showed a rapid, progressive cavitary lesion and pulmonary artery aneurysm. Angioinvastion of aspergillus was revealed by pathology after operative removal of left upper lobe containing the pulmonary artery aneurysm. He was treated with itraconazole.

Key Words: Invasive pulmonary aspergillosis, Chronic necrotizing pulmonary aspergillosis, Pulmonary artery aneurysm