Two cases of Pulmonary Alveolar Proteinosis Improved by Whole Lung Lavage.

Jeong, Seong Su; Kang, Dong Won; Lee, Kyu Seung; Ko, Dong Seok; Suh, Jae Chul; Kim, Keun Hwa; Kim, Jin Whan; Lee, Jung Un; Kim, Ju Ock; Kim, Sun Young

doi:1999.47.3.406

Tuberc Respir Dis > Volume 47(3); 1999 > Article

Case Report

Tuberculosis and Respiratory Diseases 1999;47(3):406-413.
DOI: https://doi.org/10.4046/trd.1999.47.3.406 Published online September 1, 1999.

Two cases of Pulmonary Alveolar Proteinosis Improved by Whole Lung Lavage.

Seong Su Jeong, Dong Won Kang, Kyu Seung Lee, Dong Seok Ko, Jae Chul Suh, Keun Hwa Kim, Jin Whan Kim, Jung Un Lee, Ju Ock Kim, Sun Young Kim

¹Department of Internal Medicine, College of Medicine, Chungnam National University, Taejon, Korea. jokim@hanbat.chungnam.ac.kr
²Department of Diagnostic Radiology, College of Medicine, Chungnam National University, Taejon, Korea.
³Department of Anesthesiology, College of Medicine, Chungnam National University, Taejon, Korea.

Abstract

Pulmonary alveolar proteinosis(PAP) is a disorder in which an insoluble, proteinaceous material, rich in phospholipid, is deposited on alveoli and bronchioles. Several cases were reported since 1986, and the numbers of patients is increasing in Korea. Although the pathogenesis and causative treatment of PAP is not well known, whole lung lavage is the only consistently successful treatment. We report 2 cases of PAP which were confirmed by open lung biopsy with electron microscopy and clinically improved by whole lung lavage with a review of literature.

Key Words: Pulmonary alveolar proteinosis, Whole lung lavage