A Case of Spontaneous Resolution of Idiopathic Mediastinal Fibrosis.

Wang, Joon Ho; Song, Kwang Seon; Kim, Hyun Jun; Song, Ki Ho; In, Haing Hwan; Choi, Su Bong; Joo, Mi Yeun; Sung, Ki Joon; Shin, Kye Chul

doi:1997.44.4.935

Tuberc Respir Dis > Volume 44(4); 1997 > Article

Case Report

Tuberculosis and Respiratory Diseases 1997;44(4):935-941.
DOI: https://doi.org/10.4046/trd.1997.44.4.935 Published online August 1, 1997.

A Case of Spontaneous Resolution of Idiopathic Mediastinal Fibrosis.

Joon Ho Wang, Kwang Seon Song, Hyun Jun Kim, Ki Ho Song, Haing Hwan In, Su Bong Choi, Mi Yeun Joo, Ki Joon Sung, Kye Chul Shin

Abstract

Mediastinal fibrosis is pathologically characterized by chronic inflammation and fibrosis of mediastinal soft tissue. Mediastinal fibrosis is local expression of a family of systemic fibrosing syndroms. This can result in compression of adjacent mediastinal structures. Idiopathic fibrosing syndromes include retroperitoneal fibrosis, sclerosing cholangitis of the orbit and fibrosis of the thyroid gland(Riedel's struma). The cause of these disorders is obscure, in some instance there is an underlying malignancy, infection, history of drug ingestion, or trauma with retoperitoneal bleeding. Treatment of mediastinal fibrosis depends on structures involved by the fibrotic process. The disease is self limited in most case or improved by steroids uses. We experienced a case of idopathic solerosing mediastinitis with orbital fibrous dysplasia of unknown cause, which was confirmed by open lung biopsy, so reported it with a review of literature.

Key Words: Idiopathic mediastinal fibrosis, Orbital fibrous dysplasia, Open lung biopsy