A case report of the Pulmonary Malignant Lymphomaof the mucosa-associated lymphoid tissue(MALT).

Ohn, Joon sang; Son, Hyung dae; Kim, Chang seon; Lee, Young sil; Yoon, Sang won; Rheu, Nam soo; Cho, Dong ill

doi:1996.43.6.1019

Tuberc Respir Dis > Volume 43(6); 1996 > Article

Case Report

Tuberculosis and Respiratory Diseases 1996;43(6):1019-1027.
DOI: https://doi.org/10.4046/trd.1996.43.6.1019 Published online December 1, 1996.

A case report of the Pulmonary Malignant Lymphomaof the mucosa-associated lymphoid tissue(MALT).

Joon sang Ohn, Hyung dae Son, Chang seon Kim, Young sil Lee, Sang won Yoon, Nam soo Rheu, Dong ill Cho

Department of Chest Medicine, National Medical Center, Seoul, Korea.

Abstract

The pulmonary lymphomas were thought to originate in specialized lymphoid tissue that is associated with bronchial mucosa(bronchus-associated lymphoid tissue(BALT)), and they were categorized as mucosa-associated lymphoid tissue(MALT) lymphoma. MALT lymphoma consists of a monoclonal population of cell, in contrast to reactive lymphoid proliferation, which consists of polyclonal cells. Lymphoma arising from MALT(=MALToma) represents a distinct clinicopathologic features. It is usually localized to their original site for a long time and shows much more favorable prognosis than lymphoma at other site. Some MALT lymphoma could arise simultaneously or successively in different organ or that cells from MALT lymphoma might circulate and give rise to another lymphoma by homing in the MALT of another organ, such as breast, salivary gland, stomach etc, and can be multifocally disseminated or recurred. We report a case of low-grade B-cell lymphoma of the mucosa-associated lymphoid tissue(MALT) of the lung, which was confirmed by open lung biopsy, immunohistochemistry and PCR assay.

Key Words: Lung, B-cell, Lymphoma, Mucosa-associated lymphoid tissue(MALT), Bronchus- associated lymphoid tissue(BALT), Polymerase chain reaction(PCR), Immunohistochemistry