| Clinical study on primary mediastinal tumors and cysts : report of 344 cases. |
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Hong Lyeol Lee1, Se Kyu Kim1, Hae Kyun Kim2, Kyung Young Chung2, Doo Yun Lee2, Sung Eun Kim1, Joon Chang1, Sung Kyu Kim1, Won Young Lee1 |
1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
2Department of Thoracic and Cardovascular Surgery, Yonsei University College of Medicine, Seoul, Korea |
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| Abstract |
Background
Mediastinal masses are not uncommon, and an overall inιidenιe of one case per 100, 000 population per year in individuals of all ages and with no difference in sex incidence may be a reasonable estimation. At least half of all mediastinal masses are asymptomatic and this proportion has increased in recent decades with wider use of screening chest roentgenography. Symptoms in patients with mediastinal mass lesions are usually due to compression or invasion of nearby intrathoracic structures. Most mediastinal mass lesions have characteristic predilectional locations. The basic focus of diagnostic evaluation is an orderly preparation for obtaining a tissue diagnosis but even lesions discovered to be benign must generally be removed. Seldom is this status known for certain preoperatively. In additaion, benign tumors may continue to enlarge, thus compromising vital organs; they may rupture, hemorrhage, become infected or have the possibility of various malignant degeneration. Therefore, all mediastinal masses must be surgically removed whether they are malignant or
benign.
Methods
We reviewed the medical records of 344 cases previously confirmed as mediastinal tumors or cysts from January, 1960 to August, 1992 and investigated the clinical findings.
Results
Neurogenic tumors were the most common (24.7%) and thymomas were distinctively increased recently. Overall ratio between males and females was 1.1 : 1 and age distribution was relatively even among all age groups. Predilectional sites were posterior for neurogenic tumors, and anterior for teratodermoid tumors, thymomas and lymphomas. Dyspnea was the most common symptom in the patients of the mediastinal tumors and asymptomatic patients were 19.5%, Benign mediastinal mass lesions were 66.0% and malignant, 34.0% , Complete or partial resection was done in 42.4% .
Conclusion
We could find the increasing incidence and the tendency of aggressive resection as possible in the mediastinal tumors. We expect the discovery of more mediastinal tumors with wider use of regular check-up and development of diagnostic methods. |
| Key Words:
Mediastinal tumors and cysts, Location, Resection, Debulking |
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