Tuberc Respir Dis > Volume 39(6); 1992 > Article
Tuberculosis and Respiratory Diseases 1992;39(6):536-541.
DOI:    Published online December 1, 1992.
A case of idiopathic bronchiolitis obliterans organizing pneumonia.
Cheol Whan Lee1, Youn Suck Koh1, Woo Sung Kim1, Kyeong Yub Gong2, Kun Sik Song3, Won Dong Kim1
1Department of lnternal Medicine, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea
2Department of Pathology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea
3Department of Diagnostic Radiology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea
Bronchiolitis obliterans organizing pneumonia (BOOP) is a type of diffuse interstitial lung disease that primarily affects the small conducting airways and characterized by the presence of granulation tissue plugs within the lumen of small airways often extending into alveolar ducts. It is associated with a number of different causes, including a variety of infections, fume exposures, drugs, collagen diseases and idiopathic. Recently we have experienced one patient with idiopathic BOOP The patient was a 58-year-old man presented with 2 months' history of dry cough and exertional dyspnea The physical examination showed inspiratory crackles at both lower lung field. Chest -.ray showed bilateral multiple patchy alveolar density. Pulmonary function studies showed a moderate degree of restrictive lung disease Open lung biopsy carried out and revealed findings characteristic of BOOP. There was a dramatic response clinically and radiologically to high dose prednisolone therapy. Chest X-ray and pulmonary function test under-taken one year later showed marked improvement. New lesion on chest PA was developed during the period of tapering of prednisolone dose, but it was soon disappeared after increasing of prednisolone dose. One year later, he is well without steroid therapy
Key Words: Idiopathic bronchiolitis obliterans organzing pneumonia

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