Tuberc Respir Dis > Volume 38(3); 1991 > Article
Tuberculosis and Respiratory Diseases 1991;38(3):280-286.
DOI: https://doi.org/10.4046/trd.1991.38.3.280    Published online September 1, 1991.
Clinical study of dark-blue pigmentation in the bronchial mucosa.
In Won Park, Chul Gyu Yoo, O Jung Kwon, Young Whan Kim, Sung Koo Han, Young Soo Shim, Keun Youl Kim, Yong Chol Han
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
Abstract
Dark-blue pigmentation has been thought to be related to smoking or occupational exposure and has been regarded as anthracitic pigmentation. It is also frequently observed in non-smokers without occupational exposure, but there is no proven mechanism of pigmentation. To investigate clinical features and to find other causes of dark-blue pigmentation, retrospective analysis was done in 59 patients who showed anthracitic pigmentation on bronchoscopy during recent 5 years in Seoul National Unversity Hospital. The results were as follows; 1) Forty cases were non-smokers, while smokers were 19 cases. 2) Fifteen cases had history of tuberculosis, but there was no history of environmental exposure. 3) Mediastinal calcification was observed in 89.7% . 4) There was significant bleeding without exception when biopsy was done at the pigmentation site. 5) In patients with pigmentation only, hemoptysis and productive cough were main chief complaints, and chest X-ray showed atelectasis, infiltration, mass, or pleural change 6) The number of patients whose lesion of X-ray corresponds to pigmentation site were 19/ 30 in tuberculosis, 4/ 30 in DILD and 7/ 30 in other diseases.


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