The primary mediastinal liposarcoma with effusion.

Won, Gu Tae; Park, Jin Hyun; Hong, Uk Kyun; Lee, Jae Kab; Yong, Suk Joong; Shin, Kye Chul; Jin, So Young; Jung, Soon Hee

doi:1991.38.1.65

Tuberc Respir Dis > Volume 38(1); 1991 > Article

Case Report

Tuberculosis and Respiratory Diseases 1991;38(1):65-69.
DOI: https://doi.org/10.4046/trd.1991.38.1.65 Published online March 1, 1991.

The primary mediastinal liposarcoma with effusion.

Gu Tae Won¹, Jin Hyun Park¹, Uk Kyun Hong¹, Jae Kab Lee¹, Suk Joong Yong¹, Kye Chul Shin¹, So Young Jin², Soon Hee Jung²

¹Department of Internal Medicine, Wonju University, Yonsei University, Won ju, Korea
²Department of Histopathology, Wonju University, Yonsei University, Won ju, Korea

Abstract

Primary liposarcoma of the mediastinum is a very rare and relatively slow growing tumor. Since the original description by Pallase and Roubier in 1916, there have been about 55 reported cases in world literature until 1985. Recently, we experienced one case of a primary mediastinal liposarcoma with malignant effusion A 51 -year-old man complained of dyspnea and chest discomfort. The chest plain films and computerized tomogram showed a huge mass of the posterior mediastinal space. The needle aspiration biopsy was done in the huge mass and the histologic examination revealed mediastinal round-cell type liposarcoma. Patient refused surgery or chemotherapy after establishing the diagnosis. About 6 months later, the metastatic pleural effusion was noted. After discharge, he was lost to follow up since then. The clinical and therapeutic features of the previously reported cases of primary liposarcoma arising in the mediastinum have been reviewed Surgery may serve to establish a tissue diagnosis, to relieve the patient’s symptoms and result occasionally in a cure but radiotherapy or chemotherapy is ineffective.