Studies on the Open-negative Syndrome and Pathological Open Healing

Chang, Pyoung Ha

doi:1961.0.10.55

Tuberc Respir Dis > Issue 10; 1961 > Article

Tuberculosis and Respiratory Diseases 1961;10:55-64.
DOI: https://doi.org/10.4046/trd.1961.10.1.55 Published online December 1, 1961.

Studies on the Open-negative Syndrome and Pathological Open Healing

Pyoung Ha Chang

Transportation Sanatorium, Masan, Korea

소위 Open-Negative Syndrome과 결핵성공동의 병리학적 치유에 관하여

장병하

Abstract

Three cases of pulmonary tuberculosis with formation of cystic cavities and a case of openly and pathologically healed tuberculous cavity are presented. The persistence of a smooth and thin walled cavity in the roentgenogram with the disappearance of tubercle bacilli from the sputum and gastric washings over six months are the criteria for the open-negative syndrome and free of necrotic contents or pyogenic membrane in the lumen of the cavity and transformed cavity wall into a layer of connective tissue are the criteria for the pathological open healing. The choice of whether these cavitary lesions are to be treated surgically or observed on a long-term medical program must be individualized on the merits and status of each case.