Trial of Short Course Chemotherapy for Pulmonary Tuberculosis

Yun, Kwang Sun; Hue, Sung Ho; Kim, Sun Young; Noh, Yong Ho; Kim, Yoo Young; Han, Yong Chul

doi:1978.25.4.161

Tuberc Respir Dis > Volume 25(4); 1978 > Article

Original Article

Tuberculosis and Respiratory Diseases 1978;25(4):161-164.
DOI: https://doi.org/10.4046/trd.1978.25.4.161 Published online December 1, 1978.

Trial of Short Course Chemotherapy for Pulmonary Tuberculosis

Kwang Sun Yun, Sung Ho Hue, Sun Young Kim, Yong Ho Noh, Yoo Young Kim, Yong Chul Han

Department of lnternal Medicine, College of Medicine, Seoul National University, Seoul, Korea

폐결핵 치료에 있어서 단기요법의 시도

윤광선, 허성호, 김선영, 노용호, 김유영, 한용철

Abstract

A clinical trial of nine months conbined chemotherapy including rifampicin for initial case of pulmonary tuberculosis proven by sputum AFB smear positive in 50 patients was done and its results was compared with that of a standard regimen of isoniazid, streptomycin, PAS or ethambutal in 50 patients. The results is as follows. 1. Chemotherapy failure during therapy was noticed in three patients in only standard regimen. 2. Follow up to six months after stop chemotherapy was done. There was one relaps in rifampicin containing regimen and also one relaps in standard regimen was noticed. 3. Hepatic dysfunction is more prevalent in rifampicin containing regimen.