Tuberc Respir Dis > Volume 29(4); 1982 > Article
Tuberculosis and Respiratory Diseases 1982;29(4):196-204.
DOI: https://doi.org/10.4046/trd.1982.29.4.196    Published online December 1, 1982.
Measurement of Airway Resistance in Bronchial Asthma and in Emphysema-Chronic Bronchitis
Sung Koo Han, Myung Hae Lee, Young Hyun Lee, Young Soo Shim, Keun Youl Kim, Yong Chul Han
Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea
기관지천식과 만성 기관지염 일폐기종에서의 기도저항에 관한 연구
한성구, 이명혜, 이영현, 심영수, 김건열, 한용철
Abstract
Simultaneous measurement of airway resistance and maximal expiratory flow-volume loop was performed in 20 asthmatics, 20 emphysema-chronic bronchitis patients and 10 normal control subjects. The airway resistance was both increased in asthma and in emphysema-chronic bronchitis. While the degree of decrease in the parameters of expiratory flow rate was not different in both conditions, airway resistance was significantly higher in asthma than in emphysemachronic bronchitis. The mean age of asthmatics was younger than that of emphysema-chronic bronchitis. (47. 5 vs 59.9) But there was no relationship between age and airway resistance in control group, which excludes age as a contributing factor(r= - 0.18). There was significant co-relation between Raw and FEV1/FVC, MEF 50% in asthmatics(r= - 0. 60, - 0. 67) than in emphysema-chronic bronchitis patients (r= - 0.03, - 0.20). In control group, the corelation between Raw and FEV1/FVC was fairly good (r= - 0.57), whereas corelation with MEF 50% was much poorer(r= -0.13), reflecting that the airway resistance is determined mainly by large airways, not by small airways. The Gaw, reciprocal of Raw, showed slightly {poorer corelation with parameters of expiratory flow limitation than Raw except in control group, reminding the previous finding that there can be more error in measurement of Gaw than Raw. The two cases of emphysema-chronic bronchitis patients with positive bronchodilator responce displayed higher Raw, suggesting that the measurement of Raw could be used as a predictor of bronchodilator responce.


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