Successful Treatment of Massive Pulmonary Embolism with Urokinase -A Case Report-

Lee, Kwang Hee; Song, Kyoung Il; Kwack, Jun Gu; Kim, Hyun Soo; Jung, Yun Tae; Kim, Young Hun; Park, Choon Sik

doi:1989.36.2.164

Tuberc Respir Dis > Volume 36(2); 1989 > Article

Case report

Tuberculosis and Respiratory Diseases 1989;36(2):164-170.
DOI: https://doi.org/10.4046/trd.1989.36.2.164 Published online June 1, 1989.

Successful Treatment of Massive Pulmonary Embolism with Urokinase -A Case Report-

Kwang Hee Lee, Kyoung Il Song, Jun Gu Kwack, Hyun Soo Kim, Yun Tae Jung, Young Hun Kim, Choon Sik Park

Department of Internal Medicine, Soon Chun Hyang University HosPital, Seoul, Korea

유로키나제(Urokinase)치료로 호전된 중증 폐동맥 색전증 -치험 1예-

이광희, 송경일, 곽준구, 김현수, 정연태, 김용훈, 박춘식

Abstract

Massive pulmonary embolism is a life-threatening disease that requires early accurate diagnosis and prompt management. We had a clinical experience with a case of 73-year old man who presented with abruptly developed severe dyspnea and chest discomfort accompanied with syncopal attack, that was confirmed as massive pulmonary embolism via lung scanning and pulmonary angiography. We treated the case successfully with Urokinase that is; 4,400 IU / kg IV during ten-minute period, a loading dose and 4,400IU/ kg/ hr for 12 hours, the maintenance dose, without any severe hemorrhagic complications So we report this clinical experience with review of articles.