Tuberc Respir Dis > Epub ahead of print
Miscellaneous
DOI: https://doi.org/10.4046/trd.2021.0038    [Epub ahead of print]
Published online May 13, 2021.
Revised Korean Cough Guidelines, 2020: Recommendations and Summary Statements
Hyonsoo Joo, M.D., Ph.D.1  , Ji-Yong Moon, M.D., Ph.D.2  , Tai Joon An, M.D.3, Hayoung Choi, M.D.4, So Young Park, M.D., Ph.D.5, Hongseok Yoo, M.D., Ph.D.6, Chi Young Kim, M.D.7, Ina Jeong, M.D., Ph.D.8, Joo-Hee Kim, M.D., Ph.D.9, Hyeon-Kyoung Koo, M.D., Ph.D.10, Chin Kook Rhee, M.D., Ph.D.11, Sei Won Lee, M.D., Ph.D.12, Sung Kyoung Kim, M.D., Ph.D.13, Kyung Hoon Min, M.D., Ph.D.14, Yee Hyung Kim, M.D., Ph.D.15, Seung Hun Jang, M.D., Ph.D.9, Deog Kyeom Kim, M.D., Ph.D.16, Jong Wook Shin, M.D., Ph.D.17, Hyoung Kyu Yoon, M.D., Ph.D.3, Dong-Gyu Kim, M.D., Ph.D.4, Hui Jung Kim, M.D., Ph.D.18, Jin Woo Kim, M.D., Ph.D.1 
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
2Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Seoul, Republic of Korea
3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
4Division of Pulmonary, Allergy and Critical Care Medicine, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea
5Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea
6Division of Pulmonary and Critical Care Medicine, Department of Medicine, Lung and Esophageal Cancer Center, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea
7Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
8Department of Internal Medicine, National Medical Center, Seoul, Republic of Korea
9Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea
10Divison of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea
11Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
12Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
13Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Republic of Korea
14Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea
15Department of Pulmonary, Allergy, and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Republic of Korea
16Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Republic of Korea
17Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, ChungAng University College of Medicine, Seoul, Republic of Korea
18Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Wonkwang University Sanbon Hospital, Wonkwang University School of Medicine, Gunpo, Republic of Korea
Correspondence:  Jin Woo Kim, Tel: 82-31-820-3945, Fax: 82-31-847-2719, 
Email: medkjw70@gmail.com
Received: 10 March 2021   • Revised: 10 April 2021   • Accepted: 3 May 2021
*Hyonsoo Joo and Ji-Yong Moon contributed equally to this study as co-first authors.
Abstract
Cough is the most common respiratory symptom that can have various causes. It is a major clinical problem that can reduce a patient’s quality of life. Thus, clinical guidelines for the treatment of cough were established in 2014 by the cough guideline committee under the Korean Academy of Tuberculosis and Respiratory Diseases. From October 2018 to July 2020, cough guidelines were revised by members of the committee based on the first guidelines. The purpose of these guidelines is to help clinicians efficiently diagnose and treat patients with cough. This article highlights the recommendations and summary of the revised Korean cough guidelines. It includes a revised algorithm for the evaluation of acute, subacute, and chronic cough. For a chronic cough, upper airway cough syndrome (UACS), cough variant asthma (CVA), and gastroesophageal reflux disease (GERD) should be considered in differential diagnoses. If UACS is suspected, first-generation antihistamines and nasal decongestants can be used empirically. In cases with CVA, inhaled corticosteroids are recommended to improve cough. In patients with suspected chronic cough due to symptomatic GERD, proton pump inhibitors are recommended. Chronic bronchitis, bronchiectasis, bronchiolitis, lung cancer, aspiration, intake of angiotensin-converting enzyme inhibitor, intake of dipeptidyl peptidase-4 inhibitor, habitual cough, psychogenic cough, interstitial lung disease, environmental and occupational factors, tuberculosis, obstructive sleep apnea, peritoneal dialysis, and unexplained cough can also be considered as causes of a chronic cough. Chronic cough due to laryngeal dysfunction syndrome has been newly added to the guidelines.
Key Words: Cough, Guideline, Korea


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