Study of Tuberculosis Contacts in Korea

Lee, Hyo Keun

doi:1963.0.15.14

Tuberc Respir Dis > Issue 15; 1963 > Article

Tuberculosis and Respiratory Diseases 1963;15:14-29.
DOI: https://doi.org/10.4046/trd.1963.15.1.14 Published online December 1, 1963.

Study of Tuberculosis Contacts in Korea

Hyo Keun Lee

Chest Clinic, Severance Hospital, School of Medicine, Yonsei University, Seoul, Korea

Abstract

In the absence of specific therapy, physicians applied general measures to children with a primary tuberculous infection, hoping that the undesirable consequences of the infection could be prevented by increased those resistance and by removal from the source of infection. Since the introduction of specific drugs great advances in the treatment of tuberculosis have been made. As antimicrobial therapy was extended to children with active primary tuberculosis, excellent results were obtained and it was observed that meningitis apparently did not develop among children whose treatment included INH. This observation changed the emphasis from treatment to prevention. The purpose of this study is to evaluate the effectiveness of INH secondary chemoprophylaxis on householder contact children of cases of pulmonary tuberculosis.