Immunological Effects of Korea B.C.G. upon Tuberculin Allergy

lm, Young Ho; Suh, Inn Soo

doi:1964.0.18.23

Tuberc Respir Dis > Issue 18; 1964 > Article

Tuberculosis and Respiratory Diseases 1964;18:23-28.
DOI: https://doi.org/10.4046/trd.1964.18.1.23 Published online December 1, 1964.

Immunological Effects of Korea B.C.G. upon Tuberculin Allergy

Young Ho lm, Inn Soo Suh

Department of Microbiology, Soo Do Medical College, Seoul, Korea

Abstract

This observation was made for the immunological effects of the B.C.G. administration upon tuberculin allergy on primary school children in the area of Jun Joo city, south Kyungsan province from 1962. to 1963. Both of Toberculin and B.C.G. liquid vaccine in this study were prepared in the National Institute of Health, Seoul, Korea. Tuberculin test with mantoux reaction, 5 T.U. were used. Of 2,899 boys and 2,417 girls, the age group of six to thirteen years old, the positive tuberculin rate was 26.3% and 23.8% respectively, showing no considerable difference by sex and higher positive rate almost according to their older age of group. The positive conversion rate were 80.7% after five months by the inoculating the B.C.G. 0.04mg/0.1ml, intradermally and 29.9% after 12 months. These results indicate that the B.C.G. immunity can not be long lasting one and among those who were shown positive after five months of BCG inoculation, about 50% must be administrated. The author also studied the role of tuberculosis patient for the infectivity to his own family and found out there was considerable significance in tuberculin positive late between tuberculous and non-tuberculous families, especially in the age group of six to twenty-five years in above locality.