| Home High-Flow Nasal Cannula in Patients with Chronic Respiratory Failure: A Literature Review and Suggestions for Clinical Practice |
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Youjin Chang, M.D., Ph.D.1, Moon Seong Baek, M.D., Ph.D.2, Sei Won Kim, M.D., Ph.D.3, Su Hwan Lee, M.D., Ph.D.4, Jung Soo Kim, M.D.5, So Young Park, M.D., Ph.D.6, Jin Woo Kim, M.D., Ph.D.7, Jae Hwa Cho, M.D., Ph.D.8, Sunghoon Park, M.D., Ph.D.9 |
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University College of Medicine, Sanggye Paik Hospital, Seoul, Korea
2Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
3Department of Pulmonary, Critical Care and Sleep Medicine, Eunpyeong St. Mary's Hospital, The Catholic University of Korea
4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
5Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inha University Hospital
6Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangdong Sacred Heart Hospital, Seoul, Republic of Korea
7Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
8Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
9Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, Gyeonggi-do, Republic of Korea |
Correspondence:
Sunghoon Park, Tel: (+82)-31-380-3715, Fax: (+82)-31-380-3973,
Email: f2000tj@gmail.com
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Received: 22 December 2024 • Revised: 8 February 2025 • Accepted: 12 February 2025 |
| Abstract |
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High-flow nasal cannula (HFNC) is a noninvasive respiratory support system that delivers heated (31–38℃), humidified (100%), and oxygen-enriched air at a constant high flow rate (15–60 L/min). Due to its numerous physiological benefits, with added convenience and minimal side effects, HFNC has been increasingly used in patients with acute hypoxemic respiratory failure over the past decade. However, the clinical benefits of long-term HFNC remain uncertain. Several studies, though, suggest its potential use as an alternative home oxygen therapy for patients with chronic stable lung diseases such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, and bronchiectasis. The use of long-term home HFNC in patients with chronic respiratory failure is an emerging area with promising potential. Despite limited clinical research, this narrative review aims to describe the physiology of HFNC use and summarize the current evidence on its long-term application. It provides healthcare providers with insights and perspectives on the potential role of long-term home HFNC. |
| Key Words:
High flow nasal cannula, home, oxygen, chronic lung disease |
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