| Korean Guidelines for Diagnosis and Management of Interstitial Lung Disease: Cryptogenic organizing pneumonia |
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Yong Suk Jo1, Jong Sun Park2, Sun Hyo Park3, Joon Sung Joh4, Hye Jin Jang5, Hyun-Kyung Lee6, on behalf of Korean Interstitial Lung Disease Study Group |
1Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
2Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
3Division of Pulmonology, Respiratory Center, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea
4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Medical Center, Seoul, Republic of Korea
5Division of Pulmonology, Department of Internal Medicine, Inha University Hospital, Inha University College of Medicine, Incheon, Republic of Korea
6Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, Republic of Korea |
Correspondence:
Hyun-Kyung Lee, Tel: +82-051-890-6847, Fax: 051-890-6341,
Email: goodoc@gmail.com
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Received: 4 November 2024 • Revised: 24 January 2025 • Accepted: 13 March 2025 |
| Abstract |
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Cryptogenic organizing pneumonia (COP), one of the idiopathic interstitial pneumonias (IIP), exhibits an acute or subacute course. It can be diagnosed after excluding secondary causes or diseases. COP accounts for approximately 5-10% of IIPs, with the average age of diagnosis ranging from 50 to 60 years. Patients primarily present with dry cough and dyspnea. They often experience fever, fatigue, and weight loss. Common radiologic findings on high-resolution computed tomography (HRCT) include localized consolidations, which are typically subpleural or located in the lower zones, though they can occur in all regions of the lungs. While treatment can be initiated without histopathological diagnosis, tissue biopsy may be necessary when the diagnosis is unclear. Response to steroid therapy is generally good, with rapid clinical improvement and a favorable prognosis, although relapses are common. |
| Key Words:
Interstitial Lung Disease, cryptogenic organizing pneumonia |
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