A Case of Small Cell Lung Cancer Coexisting with Chronic Lymphocytic Leukemia.

Song, June Seok; Lee, Gun Hwa; Lee, Min Kyu; Kim, Woong Jun; Lee, Seung Ho; Kim, Sang Heon; Kim, Tae Hyung; Yoon, Ho Joo; Shin, Dong Ho; Park, Sung Soo; Choi, Jung Hye; Oh, Young Ha; Sohn, Jang Won

doi:2011.71.6.454

Tuberc Respir Dis > Volume 71(6); 2011 > Article

Case Report

Tuberculosis and Respiratory Diseases 2011;71(6):454-458.
DOI: https://doi.org/10.4046/trd.2011.71.6.454 Published online December 1, 2011.

A Case of Small Cell Lung Cancer Coexisting with Chronic Lymphocytic Leukemia.

June Seok Song, Gun Hwa Lee, Min Kyu Lee, Woong Jun Kim, Seung Ho Lee, Sang Heon Kim, Tae Hyung Kim, Ho Joo Yoon, Dong Ho Shin, Sung Soo Park, Jung Hye Choi, Young Ha Oh, Jang Won Sohn

¹Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. jwsohn@hanyang.ac.kr
²Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.

Abstract

Chronic lymphocytic leukemia (CLL) is the most common type of leukemia occurring in Western nations. In CLL it is well known that the risk of a secondary malignancy is higher than in the normal population. But in Korea, CLL is a rare type of leukemia, so there have been only a few reported cases with a secondary malignancy. CLL is characterized by progressive defects in both cell-mediated and humoral immunity. It is known that defects in the immune system of patients with CLL contribute to the development of a secondary malignancy. We experienced a case of a 71-year-old man who suffered from a chronic cough and was diagnosed with small cell lung cancer coexisting with CLL. Until this case, there was no reported case in Korea of small cell lung cancer coexisting with CLL. We now report a case of small cell lung cancer coexisting with CLL and present a literature review.

Key Words: Leukemia, Lymphocytic, Chronic, B-Cell, Small Cell Lung Carcinoma