A Case of Common Variable Immune Deficiency Presenting as Recurrent Pneumococcal Pneumonia.

Jeong, Juhong; Cho, Jae Hwa; Nam, Haesung; Ryu, Jeong Seon; Kwak, Sung Min; Lee, Hong Lyeol

doi:2011.71.4.282

Tuberc Respir Dis > Volume 71(4); 2011 > Article

Case Report

Tuberculosis and Respiratory Diseases 2011;71(4):282-285.
DOI: https://doi.org/10.4046/trd.2011.71.4.282 Published online October 1, 2011.

A Case of Common Variable Immune Deficiency Presenting as Recurrent Pneumococcal Pneumonia.

Juhong Jeong, Jae Hwa Cho, Haesung Nam, Jeong Seon Ryu, Sung Min Kwak, Hong Lyeol Lee

Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea. Jaehwa.Cho@inha.ac.kr

Abstract

Common variable immune deficiency (CVID) is the most common primary immune deficiency, which is manifested as chronic recurrent respiratory infections and hypoglobulinemia. CVID usually presents in the second or third decade of life. A 33-year-old woman was admitted with recurrent pneumococcal pneumonia with bacteremia and had very low levels of serum immunoglobulin G, M and A. This case emphasized a high index of suspiciousness for diagnosis of CVID in a mid-adulthood patient presenting with recurrent pneumonia with hypoglobulinemia.

Key Words: Common Variable Immunodeficiency, Pneumonia, Pneumococcal, B-Lymphocytes