Lymphoid Interstitial Pneumonia Associated with Primary Sjogren's Syndrome: A Case Report.

Mo, Sang Il; Lee, Hyeok Gyu; Cho, A Ra; Chung, Hye Kyoung; Lee, Ho Sung; Choi, Jae Sung; Seo, Ki Hyun; Nah, Seong Su; Kim, Yong Hoon; Na, Ju Ock

doi:2010.69.5.375

Tuberc Respir Dis > Volume 69(5); 2010 > Article

Case Report

Tuberculosis and Respiratory Diseases 2010;69(5):375-380.
DOI: https://doi.org/10.4046/trd.2010.69.5.375 Published online November 1, 2010.

Lymphoid Interstitial Pneumonia Associated with Primary Sjogren's Syndrome: A Case Report.

Sang Il Mo, Hyeok Gyu Lee, A Ra Cho, Hye Kyoung Chung, Ho Sung Lee, Jae Sung Choi, Ki Hyun Seo, Seong Su Nah, Yong Hoon Kim, Ju Ock Na

Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea. Juokna@hanmail.net

Abstract

Lymphoid interstitial pneumonia (LIP) is a rare benign lymphoproliferative interstitial lung disease. LIP has been associated with autoimmune disorders, HIV, viral infections, and so on. Once underlying systemic diseases have been excluded, a diagnosis of idiopathic LIP can be made. Although 6 cases of pathologically confirmed LIP have occurred in Korea, thus far none has been associated with primary Sjogren's syndrome. A 44-year-old man was admitted to hospital due to a dry cough and dypsnea on exertion that had been ongoing for 2 months. A chest radiography showed multiple and variable-sized cystic lesions, on both lungs and both interstitial infiltration and consolidation in both lower lung fields. Tests for autoantibody showed positive results of anti-nuclear antibody and anti-Ro/La antibody. The patient underwent a video assisted thoracoscopic surgery biopsy and pathologically confirmed LIP. We report the first known case of LIP-associated with primary Sjogren's syndrome in Korea.

Key Words: Sjogren's Syndrome, Lung Diseases, Interstitial, Lymphoid Interstitial Pneumonia