| A Case of Extensive Stage Small Cell Lung Cancer Presenting as an Acute Appendicitis with Perforation. |
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Dong Won Shin, Moon Han Choi, Seung Sik Park, Sung Woo Park, Ki Up Kim, An Soo Jang, Choon Sik Park, Cheol Wan Lim, Eun Suk Ko, Sang Hyun Paik, Do Jin Kim |
1Department of Internal Medicine, Bucheon Hospital, Soonchunhyang University School of Medicine, Bucheon, Korea. kdj@schbc.ac.kr
2Department of Surgery, Bucheon Hospital, Soonchunhyang University School of Medicine, Bucheon, Korea.
3Department of Pathology, Bucheon Hospital, Soonchunhyang University School of Medicine, Bucheon, Korea.
4Department of Radiology, Bucheon Hospital, Soonchunhyang University School of Medicine, Bucheon, Korea. |
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| Abstract |
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The incidence of appendiceal metastatic cancer is quite low. In particular, in small cell lung cancer, there is a very low incidence of a metastasis to the appendix. A 75-years old man with right lower quadrant pain, cough and sputum was transferred to our hospital. Abdominal CT revealed acute appendicitis with a perforation. The patient underwent surgery. The frozen sections of the tissue obtained during surgery, indicated a malignancy, but a right hemicolectomy was not performed due to the patient's poor general condition. The histology findings of the appendix were identified as a small cell carcinoma. The abdominal CT scan and chest x-ray at admission day showed a mass in the right lower lobe, and a further evaluation of the lesion was performed including positron emission tomography and flexible bronchoscopy with a biopsy. The pathology findings of the lung mass were also small cell lung cancer. The specimens from both sites stained positive for cytokeratin, cluster designation 56, synaptophysin, chromogranin-A and thyroid transcription factor 1. It was concluded that the appendiceal small cell cancer originated from the lung. |
| Key Words:
Appendix, Metastasis, Small cell carcinoma |
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