Serum Prostaglandin Concentrations in Allergic Respiratory Diseases

Kim, You Young

doi:1982.29.3.148

Tuberc Respir Dis > Volume 29(3); 1982 > Article

Original Article

Tuberculosis and Respiratory Diseases 1982;29(3):148-151.
DOI: https://doi.org/10.4046/trd.1982.29.3.148 Published online September 1, 1982.

Serum Prostaglandin Concentrations in Allergic Respiratory Diseases

You Young Kim

Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea

호흡기 알레르기 질환에서의 혈청 Prostaglandin 농도

김유영

Abstract

The concentrations of serum prostaglandin E and F_2α were measured by radioimmunoassay in 18 patients with bronchia1 asthma, 18 with allergic rhinitis, 17 with bronchial asthma and allergic rhinitis and in 20 normal subjects. The results were as follows. 1) Serum PGE concentrations were 32. 0±5. 1 ng/ml in normal subjects and the serun PGE concentratstions of bronchial asthma patients with or without allergic rhinitis were lower than those of normal subjects. 2) Serum PGF_2α concentrations were 4. 4±0. 7 ng/ml in normal subjects and there were no differences between the serum PGF_2α concentrations of normal subjects and those of bronchial asthma or allergic rhinitis patients. 3) PGE/F ratios were 7. 4±1. 8 in normal subjects and PGE/F ratios of bronchial asthma or allergic rhinitis were lower than those of normal subjects.