Tuberc Respir Dis > Volume 52(6); 2002 > Article
Tuberculosis and Respiratory Diseases 2002;52(6):645-650.
DOI:    Published online June 1, 2002.
A Case of Dedifferentiated Chondrosarcoms: It was Changed From a Hamartoma.
Hak Ryul Kim, Sei Hoon Yang, Eun Taek Jung
Department of Internal Medicine, College of Medicine, Wonkwang University, Iksan, Korea.
Extraosseous pulmonary chondrosarcoma is a rare neoplasm, which is characterized into two groups. One is termed a primary chondrosarcoma, and arise de novo (bronchial cartilage), the other is termed a secondary chondrosarcoma, and is superimposed on preexisting benign cartilagenous neoplasms, such as a chondroma or hamartoma. The preferred treatment is surgical resection. We recently experienced a secondary chondrosarcoma changed from a hamartoma.A 54-year-old woman was referred to our hospital becaused of an abnormal chest X-ray with mild dyspnea. We performed a percutaneous transthoracic needle biopsy and sputum examination. The abnormal mass had been diagnosed as a chondromatous hamortoma wit active pulmonary tuberculosis, which had been treated with anti-tuberculosis regimens. Despite her medication, and abnormal mass had grown. Therefore, we undertook a pneumonectomy with chest wall reconstruction.Histopathologically, the mass was grade II, dedifferenciated chondrosarcoma, with chronic granulomatous inflammation and necrosis.We suggest this case had changed from a chondromatous hamartoma to a dedifferentiated chondrosarcoma, with associated pulmonary tuberculosis. We report this case with a brief literature review.
Key Words: Dedifferentiated chondrosarcoms, Hamartoma

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