Diagnostic Value of Technetium <sup>99</sup>m-DTPA Radioaerosol Ventilation Scan in a Variety of Endobronchial Diseases

Ra, Hyun; Suh, Gook Won; Hong, Won Kee; Park, Choon Sik; Choi, Deuk Lin; Kim, Gi Jeong

doi:1985.32.4.245

Tuberc Respir Dis > Volume 32(4); 1985 > Article

Original Article

Tuberculosis and Respiratory Diseases 1985;32(4):245-251.
DOI: https://doi.org/10.4046/trd.1985.32.4.245 Published online December 1, 1985.

Diagnostic Value of Technetium ⁹⁹m-DTPA Radioaerosol Ventilation Scan in a Variety of Endobronchial Diseases

Hyun Ra¹, Gook Won Suh¹, Won Kee Hong¹, Choon Sik Park¹, Deuk Lin Choi², Gi Jeong Kim²

¹Department of Internal Medicine, Soon Chun Hyang University Hospital, Seoul, Korea
²Department of Radiology, Soon Chun Hyang University Hospital, Seoul, Korea

기관지내 병변이 있는 환자에서 환기폐주사 및 관류폐주사의 임상적 의의

나현¹, 서국원¹, 홍원기¹, 박춘식¹, 최득린², 김기정²

Abstract

To evaluate the diagnostic value of Tc⁹⁹m-DTPA radioaerosol ventilation scan for prediction of the site and the character of endobronchial lesion and indirect prediction of ventilation-perfusion mismatch, we obtained Tc⁹⁹m-DTPA radioaerosol ventilation scan and Tc⁹⁹m- MAA perfusion lung scan in 8 patients of lung cancer, 3 patients of bronchiectasis, 1 patient of endobronchial tuberculosis and 1 patient of pneumonia. The results were as follows: 1) Sensitivity of ventilation scan according to anatomic lesion was 13 of 13 patients (100% ) and specificity was 11 of 13 patients(85%) and accuracy was 24 of 26 patients (92%). 2) Sensitivity of perfusion scan according to anatomic lesion was 13 of 13 patients (100%) and specificity was 9 of 13 patients(69%) and accuracy was 22 of 26 patients(85%). 3) In arterial blood gas analysis of matching group between ventilation scan and perfusion scan. PaO₂ was 87.25 ± 8 .77 mmHg and PaCO₂ was 35. 5±3. 79 mmHg. In mismatching group, PaO₂ was 83 ± 12.99 mmHg and PaO₂ was 36. 75±2. 5 mmHg. 4) In 2 of 8 patients with lung cancer. hot spot was noted on ventilation scan and perfusion defect in perfusion scan was noted in the corresponding region to hot spot in ventilation scan. We concluded that Tc99m radioaerosol ventilation scan may be valuable for detection of site and character of endobronchial lesion.